CP-724714

Alternative_name

2-methoxy-N-[(E)-3-[4-[3-methyl-4-(6-methylpyridin-3-yl)oxyanilino]quinazolin-6-yl]prop-2-enyl]acetamide
Description

CP-724714 is an inhibitor of erbB2 and EGFR kinases
CAS Number

537705-08-1
Structure Available

Yes
Salt Form

No
Molecular Formula

C27H27N5O3
Molecular Weight

469.53
Cell Permeable

Yes
Purity

≥98% by HPLC
Solubilities

Soluble in DMSO > 10 mM
Handling

Protect from air and light
Tag Line

A inhibitor of erbB2 and EGFR kinases
Storage Condition

-20°C
Shipping Condition

gel pack
Shelf Life

36 months
MDL Number

MFCD19687281
PubChem CID

9874913
PubChem CID Link
SMILES

CC1=NC=C(C=C1)OC2=C(C=C(C=C2)NC3=NC=NC4=C3C=C(C=C4)C=CCNC(=O)COC)C
InChi

1S/C27H27N5O3/c1-18-13-21(8-11-25(18)35-22-9-6-19(2)29-15-22)32-27-23-14-20(7-10-24(23)30-17-31-27)5-4-12-28-26(33)16-34-3/h4-11,13-15,17H,12,16H2,1-3H3,(H,28,33)(H,30,31,32)/b5-4+
InChi Key

LLVZBTWPGQVVLW-SNAWJCMRSA-N
Data Sheet Link
MSDS Available

Yes

Identity

HGNC:1366
Gene

ADAMTS13
Long gene name

ADAM metallopeptidase with thrombospondin type 1 motif 13
Synonyms gene
- C9orf8
Synonyms gene name
- a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 13
Synonyms
- VWFCP
- TTP
- vWF-CP
- FLJ42993
- MGC118899
- MGC118900
- DKFZp434C2322
GenBank acession
- AJ011374
Locus

9q34.2
Discovery year

1999-08-23
Entrez gene record

11093
Pubmed identfication
- 11557746
- 11535495
RefSeq identity
- NM_139025
Classification
- ADAM metallopeptidases with thrombospondin type 1 motif
VEGA ID

OTTHUMG00000020876
Locus Specific Databases
- LRG_544