BMS-599626
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Catalog number1614-1
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PricePlease ask
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Size1 mg
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Alternative_nameAC480
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DescriptionAn orally bioavailable pan-HER tyrosine kinase inhibitor with potential antineoplastic activity. BMS-599626 inhibits human epidermal growth factor receptors (HER) HER1, HER2 and HER4, thereby inhibiting the proliferation of tumor cells that overexpress these receptors.
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CAS Number873837-23-1
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₂₇H₂₇FN₈O₃.HCl
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Molecular Weight567.01
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Cell PermeableYes
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Purity≥99%
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SolubilitiesDMSO
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HandlingProtect from air and moisture
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Tag LineA pan-HER tyrosine kinase inhibitor
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Storage Condition-20°C
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Shipping ConditionRT
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Shelf Life24months
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PubChem CID46930994
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SMILESCC1=C2C(=NC=NN2C=C1NC(=O)OCC3COCCN3)NC4=CC5=C(C=C4)N(N=C5)CC6=CC(=CC=C6) F.Cl
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InChiInChI=1S/C27H27FN8O3.ClH/c1-17-23(34-27(37)39-15-22-14-38-8-7-29-22)13- 36-25(17)26(30-16-32-36)33-21-5-6-24-19(10-21)11-31-35(24)12-18-3-2-4-20 (28)9-18;/h2-6,9-11,13,16,22,29H,7-8,12,14-15H2,1H3,(H,34,37)(H,30,32, 33);1H/t22-;/m0./s1
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InChi KeyCOUSSRGSHIJMMN-FTBISJDPSA-N
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MSDS AvailableYes
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Gene target
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Short nameBMS-599626
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Alternative nameBMS-599626
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