G-CSF, murine recombinant
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Catalog number4095-50
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Price:
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Size50 ug
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SynonymsGranulocyte Colony-Stimulating Factor, CSF-3, MGI-1G, GM-CSF β, pluripoietin
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Alternative_namesGranulocyte Colony-Stimulating Factor, CSF-3, MGI-1G, GM-CSF β, pluripoietin
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DescriptionA cytokine that stimulates the bone marrow to produce granulocytes and stem cells
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RecombinantYes
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SourceE. coli
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Purity by SDS PAGE≥98%
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AssaySDS-PAGE
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Purity≥98%
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Biological activityThe ED₅₀ as determined by the dose-dependent stimulation of the proliferation of murine M-NFS-60 cells is < 0.05 ng/ml, corresponding to a specific activity of > 2 x 10⁷ units/mg.
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Molecular Weight19.0 kDa
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Storage Temp-20°C
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ShippingGel pack
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Shelf Life12 months
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AppearanceLyophilized protein
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Physical form descriptionSterile filtered and lyophilized from 5 mM NaCitrate, pH 4.0
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Reconstitution InstructionsReconstitute in H₂O to a concentration of 0.1-1 mg/ml. The solution can then be diluted into other aqueous buffers and store at 4°C for 1 week or –20°C for future use.
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Background InformationG-CSF is a potent stimulator of bone marrow cells, especially those of neutrophil lineage. In addition, G-CSF can enhance the survival and activate the immunological functions of mature neutrophils. Murine G-CSF is a 19.0 kDa protein containing 179 amino acid residues.
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HandlingCentrifuge the vial prior to opening.
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UsageFor Research Use Only! Not to be used in humans
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GeneGranulocyte-colony stimulating factor (G-CSF or GCSF), also known as colony-stimulating factor 3 (CSF 3), is a glycoprotein that stimulates the bone marrow to produce granulocytes and stem cells and release them into the bloodstream. Functionally, it is a cytokine and hormone, a type of colony-stimulating factor, and is produced by a number of different tissues. The pharmaceutical analogs of naturally occurring G-CSF are called filgrastim and lenograstim.
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Additional sourceRecombinants or rec. proteins
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Grouprecombinants
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Gene target
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Gene symbolCSF3, IGHV3-71, HLA-G, NCAPG, FOLR3, CSF2, SNRPG, GNAO1, CSF1, SFTA2
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Short nameG-CSF, murine recombinant
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TechniqueRecombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Alternative nameG-CSF, murine Rec.
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Alternative techniquerec
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Gene info
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Identity
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Gene
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Long gene namecolony stimulating factor 3
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Synonyms gene
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Synonyms gene name
- chromosome 17 open reading frame 33
- colony stimulating factor 3 (granulocyte)
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Synonyms
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Synonyms name
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Receptor ligands
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin heavy variable 3-71 (pseudogene)
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Synonyms gene
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Synonyms gene name
- immunoglobulin heavy variable 3-71
- immunoglobulin heavy variable 3-G pseudogene (provisional)
- immunoglobulin heavy variable 3-G (provisional)
- immunoglobulin heavy variable 3-71 pseudogene
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-04-04
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Entrez gene record
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RefSeq identity
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Classification
- Immunoglobulin heavy locus at 14q32.33
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemajor histocompatibility complex, class I, G
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Synonyms gene name
- HLA-G histocompatibility antigen, class I, G
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Synonyms name
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Locus
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Discovery year1990-09-10
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Entrez gene record
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RefSeq identity
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Classification
- C1-set domain containing
- Histocompatibility complex
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene namenon-SMC condensin I complex subunit G
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Synonyms gene name
- non-SMC condensin I complex, subunit G
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2006-09-04
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Armadillo like helical domain containing
- Condensin I subunits
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namefolate receptor gamma
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Synonyms gene name
- folate receptor 3 (gamma)
- folate receptor 3
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Synonyms
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GenBank acession
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Locus
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Discovery year1997-09-05
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecolony stimulating factor 2
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Synonyms gene name
- colony stimulating factor 2 (granulocyte-macrophage)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namesmall nuclear ribonucleoprotein polypeptide G
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Synonyms
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GenBank acession
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Locus
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Discovery year1990-06-13
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Entrez gene record
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Pubmed identfication
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Classification
- Sm spliceosomal proteins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameG protein subunit alpha o1
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Synonyms gene name
- guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
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Synonyms
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Locus
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Discovery year1988-04-24
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- G protein subunits alpha, group i
- MicroRNA protein coding host genes
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecolony stimulating factor 1
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Synonyms gene name
- colony stimulating factor 1 (macrophage)
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1986-01-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namesurfactant associated 2
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Synonyms gene
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Synonyms gene name
- surfactant associated protein G
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Synonyms
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GenBank acession
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Locus
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Discovery year2002-05-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
MeSH Data
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Name
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ConceptScope note: The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data