Setd1b polyclonal antibody
#
-
Catalog number6843-50
-
Price:
-
Size50 μl
-
-
Antibody TargetSetd1b
-
Target Alternative NameSET1B, KMT2G
-
Antibody TypePolyclonal
-
Species ReactivitiesMouse.
-
Immunogen SequencePolyclonal antibody raised in rabbit against mouse Setd1b (Set domain containing 1B), using a 3 KLH-conjugated synthetic peptides containing sequences from the central part of the protein
-
AccessionQ9UPS6
-
Gene Id23067
-
AppearanceColorless liquid
-
FormLiquid
-
FormulationIn PBS with 0.05% (W/V) sodium azide.
-
PurificationWhole Anti-Sera
-
ApplicationWestern blot, ELISA.
-
Positive ControlWestern blot: NIH3T3 and embryonic stem cells, ELISA: Peptides.
-
Application And UsagesELISA: 1:100 – 1:500, Western Blot: 1:500.
-
DescriptionSETD1B (UniProt/Swiss-Prot entry Q9UPS6) is a component of the SET1 histone methyltransferase (HMT) complex. This complex specifically methylates lysine 4 of histone H3, but only if the neighboring lysine 9 residue is not yet methylated. Methylation of H3K4 represents a specific tag for epigenetic transcriptional activation. SETD1B shows a non-overlapping localization with SETD1A, suggesting that both proteins play a specific role in the epigenetic control of chromatin structure and gene expression.
-
Storage Condition-20 °C
-
Shipping Conditiongel pack
-
Shelf Life12 months
-
UsageFor Research Use Only! Not to be used in humans.
-
HandlingThe antibody solution should be gently mixed before use.
-
Western Blot VerifiedVerified
-
Immunocytochemistry VerifiedNot Verified
-
Immunofluorescence VerifiedNot Verified
-
Immunoprecipitation VerifiedNot Verified
-
ELISA VerifiedVerified
-
ChIP VerifiedNot Verified
-
Dot Blot VerifiedNot Verified
-
Flow Cytometry VerifiedNot Verified
-
PropertiesIf you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
GroupPolyclonals and antibodies
-
AboutPolyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
-
French translationanticorps
-
Gene target
-
Gene symbolSETD1B
-
Short nameSetd1b polyclonal antibody
-
TechniquePolyclonal, Antibody, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
-
IsotypeRabbit IgG
-
Alternative nameSetd1b polyclonal (antibody to-)
-
Alternative techniquepolyclonals, antibodies
-
Gene info
-
Identity
-
Gene
-
Long gene nameSET domain containing 1B, histone lysine methyltransferase
-
Synonyms gene name
- SET domain containing 1B
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2006-02-15
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- SET domain containing
- Lysine methyltransferases
- RNA binding motif containing
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data