RSL3

  • Catalog number
    B2303-5
  • Price
    Please ask
  • Size
    5 mg
  • Alternative_name
    (1S,3R)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1-[4-(methoxycarbonyl)phenyl]-1H-pyrido[3,4-b]indole-3-carboxylic acid, methyl ester
  • Description
    RSL3 is a glutathione peroxidase 4 (GPX4) inhibitor and an inducer of ferroptosis. RSL3 increases lipid peroxidase levels in vitro and inhibits tumor formation and progression in vivo.
  • CAS Number
    1219810-16-8
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₂₃H₂₁ClN₂O₅
  • Molecular Weight
    440.88
  • Cell Permeable
    Yes
  • Purity
    ≥98% by HPLC
  • Solubilities
    DMSO (>35 mg/ml)
  • Handling
    Protect from air and light
  • Tag Line
    A glutathione peroxidase 4 (GPX4) inhibitor and an inducer of ferroptosis
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    36 months
  • MDL Number
    MFCD30187526
  • PubChem CID
    1750826
  • SMILES
    COC(=O)C1CC2=C(C(N1C(=O)CCl)C3=CC=C(C=C3)C(=O)OC)NC4=CC=CC=C24
  • InChi
    InChI=1S/C23H21ClN2O5/c1-30-22(28)14-9-7-13(8-10-14)21-20-16(15-5-3-4-6-17(15)25-20)11-18(23(29)31-2)26(21)19(27)12-24/h3-10,18,21,25H,11-12H2,1-2H3/t18-,21+/m1/s1
  • InChi Key
    TXJZRSRTYPUYRW-NQIIRXRSSA-N
  • MSDS Available
    YES
  • Gene target
    RSL3  
  • Short name
    RSL3
  • Alternative name
    RSL3
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