RSL3
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Catalog numberB2303-5
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PricePlease ask
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Size5 mg
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Alternative_name(1S,3R)-2-(2-chloroacetyl)-2,3,4,9-tetrahydro-1-[4-(methoxycarbonyl)phenyl]-1H-pyrido[3,4-b]indole-3-carboxylic acid, methyl ester
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DescriptionRSL3 is a glutathione peroxidase 4 (GPX4) inhibitor and an inducer of ferroptosis. RSL3 increases lipid peroxidase levels in vitro and inhibits tumor formation and progression in vivo.
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CAS Number1219810-16-8
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₂₃H₂₁ClN₂O₅
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Molecular Weight440.88
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesDMSO (>35 mg/ml)
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HandlingProtect from air and light
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Tag LineA glutathione peroxidase 4 (GPX4) inhibitor and an inducer of ferroptosis
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life36 months
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MDL NumberMFCD30187526
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PubChem CID1750826
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SMILESCOC(=O)C1CC2=C(C(N1C(=O)CCl)C3=CC=C(C=C3)C(=O)OC)NC4=CC=CC=C24
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InChiInChI=1S/C23H21ClN2O5/c1-30-22(28)14-9-7-13(8-10-14)21-20-16(15-5-3-4-6-17(15)25-20)11-18(23(29)31-2)26(21)19(27)12-24/h3-10,18,21,25H,11-12H2,1-2H3/t18-,21+/m1/s1
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InChi KeyTXJZRSRTYPUYRW-NQIIRXRSSA-N
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MSDS AvailableYES
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Gene target
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Short nameRSL3
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Alternative nameRSL3
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