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anti-BACE2C Antibody (CT)

anti-BACE2C Antibody (CT) is available 1 time from Biovision labs

6723-100 | anti-BACE2C Antibody (CT) size: BACE2C Antibody (CT) | 374.65 USD

Catalog number 6723-100
Supplier Biovision
Price 374.65 USD
Size BACE2C Antibody (CT)
1. Gene info
Identity 2499
Gene CTF1
Long gene name cardiotrophin 1
Synonyms
  • CT-1
  • CT1
GenBank acession
  • U43030
Locus 16p11.2
Discovery year 1995-05-01
Entrez gene record 1489
Pubmed identfication
  • 8833032
RefSeq identity
  • NM_001330
Classification
  • Interleukin 6 type cytokine family
Havana BLAST/BLAT OTTHUMG00000132413
Locus Specific Databases
  • LRG_408
Product images
    #0#.jpeg
Target of this antibody: BACE2C
Alternative names of antibody target: BACE2; AEPLC; ALP56; ASP21; Beta-secretase 2; Aspartic-like protease 56 kDa; Aspartyl protease 1; Beta-site amyloid precursor protein cleaving enzyme 2; Down region aspartic protease; Memapsin-1; Membrane-associated aspartic protease 1; Theta-secretase
Background information: Accumulation of the amyloid-beta (Abeta) plaque in the cerebral cortex is a critical event in the pathogenesis of Alzheimer's disease. Abeta peptide is generated by proteolytic cleavage of the beta-amyloid protein precursor (APP) at beta- and gamma-sites by proteases. The long-sought beta-secretase was recently identified by several groups independently and designated beta-site APP cleaving enzyme (BACE) and aspartyl protease 2 (Asp2). A BACE homolog was recently cloned and designated BACE2, Asp1, DRAP (for Down region aspartic protease), and memapsin 1. BACE2 also cleaves APP at beta-site and at a different site within Abeta. BACE2 locates on chromosome 21q22.3, the so-called 'Down critical region', suggesting that BACE2 and Abeta may also contribute to the pathogenesis of Down syndrome.
Antibody host: Rabbit
Clonality of antibody: Polyclonal
Isotype: Rabbit IgG
Clone: N/A
This antibody reacts with: Human
Immunogene sequence: This BACE2C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 310-339 amino acids from the C-terminal region of human BACE2C.
Concentration of antibody: N/A
Form of antibody: Liquid
Formulation of this antibody: 100 µl of antibody in PBS with 0.09% (W/V) sodium azide
Purification method: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
This antibody has been succesfully tested for use in following methods: Western blot, IHC
Recommended usage: Western blot: ~1:1000, IHC: ~1:50-1:100.
Storage information: Shelf time: 12 months in temp.: -20 deg.C
Shipping conditions: gel pack
How to handle this antibody: The antibody solution should be gently mixed before use.
Description This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Properties If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation anticorps
Gene targetBACE2C
Short name anti-BACE2C Antibody (CT)
Technique Antibody, anti
Alternative name antibody to-BACE2C (Antibody to) (CT)
Alternative technique antibodies
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anti-BACE2C Antibody (CT) | Technique alternative | 01012194
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