2'-Deoxy-6-thioguanosine

• Catalog number
  2828-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  2'-Deoxy-6-thio-D-guanosine;6-Thio-2'-deoxyguanosine; 6-thio-DG
• Description
  6-Thio-dG induces telomere dysfunction in telomerase-positive human cancer cells and hTERT-expressing human fubroblasts, but not in telomerase-negative cells. Treatment with 6-thio-dG results in rapid cell death for a wide variety of cancer cells, whereas normal human fibroblasts and human colonic epithelial cells are mostly unaffected.
• CAS Number
  789-61-7
• Structure Available
  Yes
• Salt Form
  M
• Molecular Formula
  C₁₀H₁₃N₅O₃S
• Molecular Weight
  283.31
• Cell Permeable
  yes
• Purity
  ≥97% by HPLC
• Solubilities
  DMSO:H₂O (1:2) (50 mM)
• Handling
  Protect from air and moisture
• Tag Line
  An anticancer agent
• Storage Condition
  -20°C
• Shipping Condition
  Gel Pack
• Shelf Life
  36 months
• MDL Number
  MFCD00672275
• PubChem CID
  3000603
• PubChem CID Link
• SMILES
  C1C(C(OC1N2C=NC3=C2NC(=NC3=S)N)CO)O
• InChi
  InChI=1S/C10H13N5O3S/c11-10-13-8-7(9(19)14-10)12-3-15(8)6-1-4(17)5(2-16)18-6/h3-6,16-17H,1-2H2,(H3,11,13,14,19)/t4-,5+,6+/m0/s1
• InChi Key
  SCVJRXQHFJXZFZ-KVQBGUIXSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Deoxy-6-thioguanosine  
• Gene symbol
  MIR1302-6, PIRC28, PIRC24, PIRC26, PIRC27, PIRC25, ADCP1
• Short name
  2'-Deoxy-6-thioguanosine
• Alternative name
  2'-Deoxy-6-thioguanosine

Gene info

• Identity
  HGNC:35298
• Gene
  MIR1302-6
• Long gene name
  microRNA 1302-6
• Synonyms gene
  • MIRN1302-6
• Synonyms
  • hsa-mir-1302-6
• Locus
  7p21.1
• Discovery year
  2008-11-03
• Entrez gene record
  100302140
• RefSeq identity
  • NR_031635
• Classification
  • MicroRNA MIR1302 family

Gene info

• Identity
  HGNC:37532
• Gene
  PIRC28
• Long gene name
  piwi-interacting RNA cluster 28
• Locus
  6
• Discovery year
  2009-11-05
• Entrez gene record
  100313893
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37528
• Gene
  PIRC24
• Long gene name
  piwi-interacting RNA cluster 24
• Locus
  6
• Discovery year
  2009-11-05
• Entrez gene record
  100313810
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37530
• Gene
  PIRC26
• Long gene name
  piwi-interacting RNA cluster 26
• Locus
  6
• Discovery year
  2009-11-05
• Entrez gene record
  100313852
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37531
• Gene
  PIRC27
• Long gene name
  piwi-interacting RNA cluster 27
• Locus
  6
• Discovery year
  2009-11-05
• Entrez gene record
  100313907
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37529
• Gene
  PIRC25
• Long gene name
  piwi-interacting RNA cluster 25
• Locus
  6
• Discovery year
  2009-11-05
• Entrez gene record
  100313851
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:229
• Gene
  ADCP1
• Long gene name
  adenosine deaminase complexing protein 1
• Locus
  6
• Discovery year
  1986-01-01
• Entrez gene record
  106
• Pubmed identfication
  • 279003
  • 6933468
  • 6974523

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