APC-Linked Polyclonal Antibody to Melanoma Cell Adhesion Molecule (MCAM)

• Catalog number
  MBS2057755
• Price
  Please ask
• Size
  0,1 mg

• Other size
  please contact us to order other different size
• Description
  cell adhesion molecules play a role in cell growth and activation and are often identified by WB or ELISA as in the APC-Linked Polyclonal Antibody Melanoma Adhesion Molecule (MCAM). For cells, cell lines and tissues in culture till half confluency. Whole adhesion and interacting molecules are  present in lysates used as reference for ELISA quantification of these molecules and their subunits.
• Properties
  If you buy Antibodies supplied by MyBioSource they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Group
  Polyclonals and antibodies
• About
  Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
• French translation
  anticorps

• Gene target
  APC-Linked   Melanoma   Adhesion   Molecule   MCAM  
• Gene symbol
  APC, MCAM
• Short name
  APC-Linked Polyclonal Antibody Melanoma Adhesion Molecule (MCAM)
• Technique
  Polyclonal, Antibody, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Label
  APC
• Alternative name
  adenomatous polyposis coli-Linked polyclonal (antibody to-) to Melanoma cellular Adhesion Molecule (melanoma cell adhesion molecule)
• Alternative technique
  polyclonals, antibodies
• Alternative to gene target
  adenomatous polyposis coli, BTPS2 and DP2 and DP2.5 and DP3 and GS and PPP1R46, APC and IDBG-37007 and ENSG00000134982 and 324, microtubule plus-end binding, nuclei, Apc and IDBG-134573 and ENSMUSG00000005871 and 11789, BT.25770 and IDBG-644937 and ENSBTAG00000018852 and 533233
• Tissue
  cell

Gene info

• Identity
  HGNC:583
• Gene
  APC
• Long gene name
  APC regulator of WNT signaling pathway
• Synonyms gene name
  • adenomatosis polyposis coli
  • adenomatous polyposis coli
  • APC, WNT signaling pathway regulator
• Synonyms
  • DP2
  • DP3
  • DP2.5
  • PPP1R46
• Synonyms name
  • protein phosphatase 1, regulatory subunit 46
• GenBank acession
  • M74088
• Locus
  5q22.2
• Discovery year
  1986-01-01
• Entrez gene record
  324
• Pubmed identfication
  • 1651563
• RefSeq identity
  • NM_000038
• Classification
  • Protein phosphatase 1 regulatory subunits
  • Armadillo repeat containing
• VEGA ID
  OTTHUMG00000128806
• Locus Specific Databases
  • Adenomatous polyposis coli mutation database
  • UMD Locus Specific Databases
  • Global Variome shared LOVD
  • APC database at LOVD-China
  • LOVD - Leiden Open Variation Database
  • LRG_130

Gene info

• Identity
  HGNC:6934
• Gene
  MCAM
• Long gene name
  melanoma cell adhesion molecule
• Synonyms
  • MUC18
  • CD146
  • MelCAM
  • METCAM
  • HEMCAM
• Synonyms name
  • Gicerin
• GenBank acession
  • X68264
• Locus
  11q23.3
• Discovery year
  1995-12-18
• Entrez gene record
  4162
• Pubmed identfication
  • 2602381
  • 10702685
  • 19229070
• Classification
  • Ig-like cell adhesion molecule family
  • C2-set domain containing
  • V-set domain containing
  • MicroRNA protein coding host genes
  • CD molecules
• VEGA ID
  OTTHUMG00000166197

MeSH Data

• Name
  Mammary Neoplasms, Experimental
• Concept
  Scope note: Experimentally induced mammary neoplasms in animals to provide a model for studying human BREAST NEOPLASMS.
• Tree numbers
  • C04.588.531.500
  • C04.619.590
  • E05.598.500.496.843
• Qualifiers
  diagnosis, parasitology, immunology, microbiology, diagnostic imaging, physiopathology, secondary, enzymology, etiology, mortality, epidemiology, blood, cerebrospinal fluid, chemically induced, congenital, diet therapy, drug therapy, therapy, chemistry, psychology, urine, virology, history, blood supply, classification, economics, embryology, genetics, nursing, radiotherapy, prevention & control, pathology, ultrastructure, metabolism, complications, surgery

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