NVP-BEP800
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Catalog numberB2198-5
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PricePlease ask
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Size5 mg
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Alternative_name2-amino-4-[2,4-dichloro-5-[2-(1-pyrrolidinyl)ethoxy]phenyl]-N-ethyl-thieno[2,3-d]pyrimidine-6-carboxamide
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DescriptionNVP-BEP800 is a potent oral inhibitor of Hsp90β (IC₅₀ = 58 nM). Displays strong anti-proliferative activity against various tumor cell lines and primary tumors in vitro and in vivo at well-tolerated doses.
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CAS Number847559-80-2
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₂₁H₂₃Cl₂N₅O₂S
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Molecular Weight480.4
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesEtOH (~5 mg/ml)
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HandlingProtect from air and light
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Tag LineA potent oral inhibitor of Hsp90β
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life36 months
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PubChem CID25210273
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SMILESCCNC(=O)C1=CC2=C(N=C(N=C2S1)N)C3=CC(=C(C=C3Cl)Cl)OCCN4CCCC4
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InChiInChI=1S/C21H23Cl2N5O2S/c1-2-25-19(29)17-10-13-18(26-21(24)27-20(13)31-17)12-9-16(15(23)11-14(12)22)30-8-7-28-5-3-4-6-28/h9-11H,2-8H2,1H3,(H,25,29)(H2,24,26,27)
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InChi KeyWJUNQSYQHHIVFX-UHFFFAOYSA-N
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MSDS AvailableYes
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Gene target
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Short nameNVP-BEP800
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Alternative nameNVP-BEP800
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