CD16, CD32 (Mouse Seroblock FcR) (Biotin)

• Catalog number
  GEN632434
• Price
  Please ask
• Size
  100ug

• Also known as
  CD16, CD32
• Other names
  N/A
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  N/A
• Gene name synonims
  N/A
• Other gene names
  N/A
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG2b
• Clone
  6A252
• Host organism
  Rat (Rattus norvegicus)
• Source organism
  Mouse (Mus musculus)
• Species reactivity
  Mouse (Mus musculus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  Recognizes an epitope expressed by the murine low affinity Fc receptors, Fc gamma III (CD16) and Fc gamma II (CD32).; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  Affinity Purified by Protein G affinity chromatography.
• Form Appearance
  Supplied as a liquid in PBS, pH 7.4, 1% BSA, 0.09% sodium azide. Conjugated to Biotin.
• Concentration
  N/A
• Storage and shipping
  Store the antibody at +4 degrees Celsius for short term storage.. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze the antibody should be stored at -20 degrees Celsius.. Aliquots are stable for at least 6 months the antibody should be stored at -20 degrees Celsius.. Prior to use, briefly centrifuge the original vial after thawing and before lid. If further dilution(s) are needed, they can be done with the appropriate assay buffer.
• Tested applications
  Flow Cytometry (FC/FACS)
• Properties
  Biotin conjugates can be detected by horseradish peroxidase, alkaline phosphatase substrates or anti biotin conjugated antibodies. Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA. To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1.6.
• Conjugation
  Biotinylated
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus

• Gene target
  CD16   CD32   Seroblock   FcR  
• Gene symbol
  FCGR3A, FCGR2B, FCGR3B, FCGR2A
• Short name
  CD16, CD32 (Mouse Seroblock FcR) ( )
• Technique
  Mouse, mouses
• Host
  mouse
• Label
  Biotin
• Species
  Mouse, Mouses
• Alternative name
  Anti-CD16, CD32 (Mouse Seroblock FcR) (Biotin)
• Alternative technique
  murine

Gene info

• Identity
  HGNC:3619
• Gene
  FCGR3A
• Long gene name
  Fc gamma receptor IIIa
• Synonyms gene
  • FCGR3
  • FCG3
• Synonyms gene name
  • Fc fragment of IgG, low affinity IIIa, receptor for (CD16)
  • Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
  • Fc fragment of IgG receptor IIIa
• Synonyms
  • CD16
  • CD16a
  • FcgammaRIIIa
  • FcGRIIIA
• GenBank acession
  • BC036723
• Locus
  1q23.3
• Discovery year
  1988-11-30
• Entrez gene record
  2214
• Pubmed identfication
  • 2139735
  • 11835346
  • 19309690
• RefSeq identity
  • NM_000569
• Classification
  • Immunoglobulin like domain containing
  • CD molecules
• VEGA ID
  OTTHUMG00000034466
• Locus Specific Databases
  • FCGR3Abase: Mutation registry for Natural killer cell deficiency
  • LRG_60

Gene info

• Identity
  HGNC:3618
• Gene
  FCGR2B
• Long gene name
  Fc gamma receptor IIb
• Synonyms gene
  • FCG2
  • FCGR2
• Synonyms gene name
  • Fc fragment of IgG, low affinity IIb, receptor for (CD32)
  • Fc fragment of IgG, low affinity IIb, receptor (CD32)
  • Fc fragment of IgG receptor IIb
• Synonyms
  • CD32
  • CD32B
  • FcgammaRIIb
  • FcGRIIB
• GenBank acession
  • BC031992
• Locus
  1q23.3
• Discovery year
  1991-08-21
• Entrez gene record
  2213
• Pubmed identfication
  • 2139735
  • 19309690
• RefSeq identity
  • NM_004001
• Classification
  • CD molecules
  • Immunoglobulin like domain containing
• VEGA ID
  OTTHUMG00000034470

Gene info

• Identity
  HGNC:3620
• Gene
  FCGR3B
• Long gene name
  Fc gamma receptor IIIb
• Synonyms gene
  • FCGR3
  • FCG3
• Synonyms gene name
  • Fc fragment of IgG, low affinity IIIb, receptor for (CD16)
  • Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
  • Fc fragment of IgG receptor IIIb
• Synonyms
  • CD16
  • CD16b
  • FcgammaRIIIb
  • FcRIIIb
• GenBank acession
  • J04162
• Locus
  1q23.3
• Discovery year
  1991-08-21
• Entrez gene record
  2215
• Pubmed identfication
  • 2139735
  • 11034564
  • 17529978
• RefSeq identity
  • NM_000570
• Classification
  • CD molecules
  • Immunoglobulin like domain containing
• VEGA ID
  OTTHUMG00000074099
• Locus Specific Databases
  • LRG_1238

Gene info

• Identity
  HGNC:3616
• Gene
  FCGR2A
• Long gene name
  Fc gamma receptor IIa
• Synonyms gene
  • FCG2
  • FCGR2A1
  • FCGR2
• Synonyms gene name
  • Fc fragment of IgG, low affinity IIa, receptor for (CD32)
  • Fc fragment of IgG, low affinity IIa, receptor (CD32)
  • Fc fragment of IgG receptor IIa
• Synonyms
  • CD32
  • CD32A
  • IGFR2
  • CDw32
  • Fc-gamma-RIIa
  • FcgammaRIIa
• Synonyms name
  • Immunoglobulin G Fc receptor II
• GenBank acession
  • J03619
• Locus
  1q23.3
• Discovery year
  1988-11-30
• Entrez gene record
  2212
• Pubmed identfication
  • 2139735
  • 8994865
• RefSeq identity
  • NM_021642
• Classification
  • Immunoglobulin like domain containing
  • CD molecules
• VEGA ID
  OTTHUMG00000034469
• Locus Specific Databases
  • LRG_1109

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