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CHIR 98014 for cell activation

CHIR 98014 for cell activation is available 2 times from Biovision labs

2595-1 | CHIR-98014 for cell activation size: 1 mg | 161.11 USD

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2595-5 | CHIR-98014 for cell activation size: 5 mg | 469.72 USD

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Other name 6-N-[2-[[4-(2,4-dichlorophenyl)-5-imidazol-1-ylpyrimidin-2-yl]amino]ethyl]-3-nitropyridine-2,6-diamine; CT 98014
Supplied with N/A
Description Cell-permeable. CHIR-98014 is a potent, selective and ATP-competitive inhibitor of GSK3α and GSK3β (IC₅₀ = 0.65 and 0.58 nM, respectively). In addition, CHIR-98014 displays 500 to greater than 1000-fold selectivity towards GSK3 than other protein kinases such as cdc2 and ERK2. CHIR98014 also reduces tau phosphorylation in rat brains and supports Wnt signaling during osteogenesis.
Category Biochemicals
Molecular formula C₂₀H₁₇Cl₂N₉O₂
Is it cell-permeable? Yes
Molecular weight 486.31
Storage condition -20 ̊C
Shipping condition Gel pack
Purification >98% by HPLC
Peptide sequence N/A
Is this a salt? No
CAS number 556813-39-9
Storage instructions Protect from air and light
Maximum time for storage 36 months
Physical appearance Crystalline solid
Reconstitute instructions DMSO (~ 4 mg/ml)
Additional description For cells, cell lines and tissues in culture till half confluency.
Short name CHIR-98014 for activation
Technique activation
Alternative name CHIR-98014 to measure cellular activation
Tissue cell
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