Thiocolchicine

  • Catalog number
    2213-5
  • Price
    Please ask
  • Size
    5 mg
  • Alternative_name
    10-Demethoxy-10-methylthiocolchicine; NSC 186301
  • Description
    An antimitotic alkaloid. Tubulin polymerization and microtubule assembly inhibitor and axonal cytoskeleton modulator; apoptosis inducer. Thiocolchicine-dimers were shown to be potent topoisomerase I inhibitors.
  • CAS Number
    2730-71-4
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₂₂H₂₅NO₅S
  • Molecular Weight
    415.5
  • Cell Permeable
    Yes
  • Purity
    ³95% by NMR
  • Solubilities
    DMSO
  • Handling
    Protect from air and light
  • Tag Line
    A tubulin polymerization and microtubule assembly inhibitor
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    24months
  • PubChem CID
    546854
  • SMILES
    CC(=O)NC1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)SC)OC)OC)OC
  • InChi
    InChI=1S/C22H25NO5S/c1-12(24)23-16-8-6-13-10-18(26-2)21(27-3)22(28-4)20(13)14-7-9-19(29-5)17(25)11-15(14)16/h7,9-11,16H,6,8H2,1-5H3,(H,23,24)
  • InChi Key
    CMEGANPVAXDBPL-UHFFFAOYSA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    Thiocolchicine
  • Alternative name
    Thiocolchicine
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