anti- HEXA antibody
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Catalog numberFNab03842
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PricePlease ask
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Size2X100μg
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Formliquid
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PurificationImmunogen affinity purified
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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BackgroundThis gene encodes a member of the glycosyl hydrolase 20 family of proteins. The encoded preproprotein is proteolytically processed to generate the alpha subunit of the lysosomal enzyme beta-hexosaminidase. This enzyme, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene lead to an accumulation of GM2 ganglioside in neurons, the underlying cause of neurodegenerative disorders termed the GM2 gangliosidoses, including Tay-Sachs disease (GM2-gangliosidosis type I). Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed.
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Immunogenhexosaminidase A (alpha polypeptide)
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Calculated MWRefer to figures
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Uniprot IDP06865
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SpecificityHuman, Mouse, Rat
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Tested ApplicationELISA, WB, IHC
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Recommended dilutionWB: 1:500 - 1:2000; IHC: 1:50 - 1:200
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Image1Immunohistochemistry of paraffin-embedded human prostate cancer using FNab03842(HEXA antibody) at dilution of 1:50
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Image4PC-3 cells were subjected to SDS PAGE followed by western blot with FNab03842(HEXA antibody) at dilution of 1:1000
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
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PropertiesIf you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolHEXA, HEXA-AS1
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Short nameanti- HEXA antibody
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TechniqueAntibody, anti, antibody to, antibodies against human proteins, antibodies for
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HostRabbit
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IsotypeIgG
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Alternative nameantibody to- HEXA (antibody to-)
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene namehexosaminidase subunit alpha
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Synonyms gene name
- hexosaminidase A (alpha polypeptide)
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Synonyms name
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GenBank acession
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Locus
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Discovery year2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Hexosaminidases
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameHEXA antisense RNA 1
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Synonyms gene
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Synonyms gene name
- chromosome 15 open reading frame 34
- HEXA antisense RNA 1 (non-protein coding)
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Synonyms
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Locus
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Discovery year2005-10-20
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Antisense RNAs
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data