NAV2 (Neuron Navigator 2, Helicase APC Down-regulated 1, Pore Membrane and/or Filament-interacting-like Protein 2, Retinoic Acid Inducible in Neuroblastoma 1, Steerin-2, Unc-53 Homolog 2, unc53H2, HELAD1, KIAA1419, POMFIL2, RAINB1, STEERIN2, FLJ10633, FLJ

• Catalog number
  GEN643398
• Price
  Please ask
• Size
  100ug

• Also known as
  NAV2
• Other names
  neuron navigator 2 isoform 4; Neuron navigator 2; neuron navigator 2; steerin-2; unc-53 homolog 2; helicase, APC down-regulated 1; retinoic acid inducible gene in neuroblastoma 1; pore membrane and/or filament-interacting-like protein 2; neuron navigator 2; Helicase APC down-regulated 1; Pore membrane and/or filament-interacting-like protein 2; Retinoic acid inducible in neuroblastoma 1; Steerin-2; Unc-53 homolog 2
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  NAV2; NAV2; HELAD1; RAINB1; POMFIL2; UNC53H2; STEERIN2; HELAD1; KIAA1419; POMFIL2; RAINB1; STEERIN2; unc53H2
• Gene name synonims
  NAV2; NAV2; HELAD1; RAINB1; POMFIL2; UNC53H2; STEERIN2; HELAD1; KIAA1419; POMFIL2; RAINB1; STEERIN2; unc53H2
• Other gene names
  NAV2; NAV2; HELAD1; RAINB1; POMFIL2; UNC53H2; STEERIN2; HELAD1; KIAA1419; POMFIL2; RAINB1; STEERIN2; unc53H2
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG2a,k
• Clone
  4D11
• Host organism
  Mouse (Mus musculus)
• Source organism
  Human (Homo sapiens)
• Species reactivity
  Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  Recognizes human NAV2.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  Affinity Purified by Protein A affinity chromatography.
• Form Appearance
  Supplied as a liquid in PBS, pH 7.2.
• Concentration
  N/A
• Storage and shipping
  Store the antibody at +4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Tested applications
  ELISA (EL/EIA), Western Blot (WB)
• Description
  Associated membrane protein types are lipopolysaccharide selective barriers. Biological membranes include cell membranes, outer coverings of cells or organelles that allow passage of certain proteins and nuclear membranes, which cover a cell nucleus; and tissue membranes, such as mucosae and serosae. 

• Gene target
  NAV2   Neuron   Navigator   Helicase   APC   Down-regulated   Pore   Membrane   Filament-interacting-like   Protein   Retinoic   Acid   Neuroblastoma   Steerin-2   Unc-53   Homolog   unc53H2   HELAD1   KIAA1419   POMFIL2   RAINB1   STEERIN2   FLJ10633   FLJ  
• Gene symbol
  NAV2, NAV2-IT1, NAV2-AS5, NAV2-AS6, NAV2-AS2, NAV2-AS3, NAV2-AS4, NAV2-AS1, APC
• Short name
  NAV2 (Neuron Navigator 2, Helicase APC Down-regulated 1, Pore / Filament-interacting-like Protein 2, Retinoic Acid in Neuroblastoma 1, Steerin-2, Unc-53 Homolog 2, unc53H2, HELAD1, KIAA1419, POMFIL2, RAINB1, STEERIN2, FLJ10633, FLJ
• Label
  APC
• Alternative name
  Anti-NAV2 (Neuron Navigator 2, Helicase APC Down-regulated 1, Pore Membrane and/or Filament-interacting-like Protein 2, Retinoic Acid Inducible in Neuroblastoma 1, Steerin-2, Unc-53 Homolog 2, unc53H2, HELAD1, KIAA1419, POMFIL2, RAINB1, STEERIN2, FLJ10633, FLJ
• Alternative to gene target
  adenomatous polyposis coli, BTPS2 and DP2 and DP2.5 and DP3 and GS and PPP1R46, APC and IDBG-37007 and ENSG00000134982 and 324, microtubule plus-end binding, nuclei, Apc and IDBG-134573 and ENSMUSG00000005871 and 11789, BT.25770 and IDBG-644937 and ENSBTAG00000018852 and 533233

Gene info

• Identity
  HGNC:15997
• Gene
  NAV2
• Long gene name
  neuron navigator 2
• Synonyms
  • FLJ10633
  • FLJ11030
  • HELAD1
  • KIAA1419
  • POMFIL2
  • RAINB1
  • FLJ23707
• Synonyms name
  • pore membrane and/or filament interacting like protein 2
  • retinoic acid inducible gene in neuroblastoma 1
  • helicase, APC down-regulated 1
• GenBank acession
  • AB037840
• Locus
  11p15.1
• Discovery year
  2001-06-29
• Entrez gene record
  89797
• Pubmed identfication
  • 12079279
  • 12062803
• RefSeq identity
  • NM_145117
• Classification
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000151837

Gene info

• Identity
  HGNC:41416
• Gene
  NAV2-IT1
• Long gene name
  NAV2 intronic transcript 1
• Synonyms gene name
  • NAV2 intronic transcript 1 (non-protein coding)
• Locus
  11p15.1
• Discovery year
  2011-05-24
• Classification
  • Intronic transcripts
• VEGA ID
  OTTHUMG00000166103

Gene info

• Identity
  HGNC:40740
• Gene
  NAV2-AS5
• Long gene name
  NAV2 antisense RNA 5
• Synonyms gene name
  • NAV2 antisense RNA 5 (non-protein coding)
• Locus
  11p15.1
• Discovery year
  2011-05-24
• Entrez gene record
  100874012
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000166104

Gene info

• Identity
  HGNC:55264
• Gene
  NAV2-AS6
• Long gene name
  NAV2 antisense RNA 6
• Locus
  11p15.1
• Discovery year
  2020-09-29
• Entrez gene record
  100126784
• RefSeq identity
  • NR_015384
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:40743
• Gene
  NAV2-AS2
• Long gene name
  NAV2 antisense RNA 2
• Synonyms gene name
  • NAV2 antisense RNA 2 (non-protein coding)
• Locus
  11p15.1
• Discovery year
  2011-05-24
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000167397

Gene info

• Identity
  HGNC:40742
• Gene
  NAV2-AS3
• Long gene name
  NAV2 antisense RNA 3
• Synonyms gene name
  • NAV2 antisense RNA 3 (non-protein coding)
• Locus
  11p15.1
• Discovery year
  2011-05-24
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000167396

Gene info

• Identity
  HGNC:40741
• Gene
  NAV2-AS4
• Long gene name
  NAV2 antisense RNA 4
• Synonyms gene name
  • NAV2 antisense RNA 4 (non-protein coding)
• Locus
  11p15.1
• Discovery year
  2011-05-24
• Entrez gene record
  399876
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000166105

Gene info

• Identity
  HGNC:40744
• Gene
  NAV2-AS1
• Long gene name
  NAV2 antisense RNA 1
• Synonyms gene name
  • NAV2 antisense RNA 1 (non-protein coding)
• Locus
  11p15.1
• Discovery year
  2011-05-24
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000167398

Gene info

• Identity
  HGNC:583
• Gene
  APC
• Long gene name
  APC regulator of WNT signaling pathway
• Synonyms gene name
  • adenomatosis polyposis coli
  • adenomatous polyposis coli
  • APC, WNT signaling pathway regulator
• Synonyms
  • DP2
  • DP3
  • DP2.5
  • PPP1R46
• Synonyms name
  • protein phosphatase 1, regulatory subunit 46
• GenBank acession
  • M74088
• Locus
  5q22.2
• Discovery year
  1986-01-01
• Entrez gene record
  324
• Pubmed identfication
  • 1651563
• RefSeq identity
  • NM_000038
• Classification
  • Protein phosphatase 1 regulatory subunits
  • Armadillo repeat containing
• VEGA ID
  OTTHUMG00000128806
• Locus Specific Databases
  • Adenomatous polyposis coli mutation database
  • UMD Locus Specific Databases
  • Global Variome shared LOVD
  • APC database at LOVD-China
  • LOVD - Leiden Open Variation Database
  • LRG_130

MeSH Data

• Name
  Gene Knockdown Techniques
• Concept
  Scope note: The artificial induction of GENE SILENCING by the use of RNA INTERFERENCE to reduce the expression of a specific gene. It includes the use of DOUBLE-STRANDED RNA, such as SMALL INTERFERING RNA and RNA containing HAIRPIN LOOP SEQUENCE, and ANTI-SENSE OLIGONUCLEOTIDES.
• Tree numbers
  • E05.393.335.500
• Qualifiers
  ethics, mortality, psychology, trends, veterinary, history, classification, economics, instrumentation, methods, nursing, standards, adverse effects, statistics & numerical data

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