Anti-BAF53B Antibody

• Catalog number
  A1620-100
• Price
  Please ask
• Size
  100 µl

• Antibody Target
  BAF53B
• Target Alternative Name
  ACTL6; BAF53B; Actin-like protein 6B; 53 kDa BRG1-associated factor B; Actin-related protein Baf53b; ArpNalpha; BRG1-associated factor 53B; BAF53B
• Antibody Type
  Polyclonal
• Species Reactivities
  Human, Mouse, Rat
• Immunogen Sequence
  Recombinant full length protein of human BAF53B
• Accession
  O94805
• Gene Id
  51412
• Appearance
  Colorless liquid
• Form
  Liquid
• Formulation
  In 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol and 0.01% sodium azide
• Purification
  Affinity purified
• Application
  WB, IHC, IF
• Positive Control
  WB: HL60; Hela; HepG2; mouse brain whole cell lysates, IHC: human brain tissue, IF: A549 cells
• Application And Usages
  WB; 1:500 – 1:1000, IH; 1:50 – 1:200, IF/IC; 1:50 – 1:100
• Description
  Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic activities, changing chromatin structure by altering DNA-histone contacts within a nucleosome in an ATP-dependent manner. Belongs to the neuron-specific chromatin remodeling complex (nBAF complex), as such plays a role in remodeling mononucleosomes in an ATP-dependent fashion, and is required for postmitotic neural development and dendritic outgrowth. During neural development a switch from a stem/progenitor to a postmitotic chromatin remodeling mechanism occurs as neurons exit the cell cycle and become committed to their adult state. The transition from proliferating neural stem/progenitor cells to postmitotic neurons requires a switch in subunit composition of the npBAF and nBAF complexes.
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  25 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Verified
• Immunofluorescence Verified
  Verified
• Immunoprecipitation Verified
  Not Verified
• FACS Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Dot Blot Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Additional description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  BAF53B  
• Gene symbol
  ACTL6B
• Short name
  Anti-BAF53B Antibody
• Technique
  Antibody, anti-, anti, antibody to, antibodies, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibody toBAF53B (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:160
• Gene
  ACTL6B
• Long gene name
  actin like 6B
• Synonyms gene
  • ACTL6
• Synonyms gene name
  • actin-like 6
• Synonyms
  • BAF53B
  • SMARCN2
• GenBank acession
  • AB015906
• Locus
  7q22.1
• Discovery year
  1998-06-01
• Entrez gene record
  51412
• Pubmed identfication
  • 9799793
• RefSeq identity
  • NM_016188
• Classification
  • PBAF complex
  • BAF complex
  • GBAF complex
  • Actin related proteins
• VEGA ID
  OTTHUMG00000159661

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

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