Human CellExp™ UNC5B, human recombinant

• Catalog number
  7576-10
• Price
  Please ask
• Size
  10 ug

• Synonyms
  Netrin Receptor UNC5B; UNC5H2; Protein Unc-5 Homolog 2; Protein Unc-5 Homolog B; p53-regulated Receptor for Death and Life Protein 1
• Alternative_names
  Netrin Receptor UNC5B; UNC5H2; Protein Unc-5 Homolog 2; Protein Unc-5 Homolog B; p53-regulated Receptor for Death and Life Protein 1
• Description
  A receptor for the netrin family of guidance molecules
• Recombinant
  Yes
• Source
  HEK293 cells
• Purity by SDS PAGE
  ≥95%
• Assay
  SDS-PAGE
• Molecular Weight
  ~80.0 kDa. The extracellular region of human UNC5B (aa 28-363) is fused at the C-terminus to the Fc portion of human IgG1.
• Storage Temp
  -20°C
• Shipping
  Gel Pack
• Shelf Life
  6 months
• Appearance
  Lyophilized
• Physical form description
  Lyophilized in PBS.
• Reconstitution Instructions
  Reconstitute with 50 ul sterile distilled water.
• Background Information
  UNC5B is a receptor for the netrin family of guidance molecules. It was identified as a mediator of the repulsive response in neurons and it is the only known netrin receptor with prominent endothelial expression. It has an important role in angiogenesis signaling.
• Handling
  Centrifuge the vial prior to opening.
• Usage
  For Research Use Only! Not to be used in humans
• Datasheet
• Properties
  Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  CellExp™   UNC5B  
• Gene symbol
  UNC5B-AS1, UNC5B
• Short name
  CellExp™ UNC5B, recombinant
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Species
  Humans
• Alternative name
  H. sapiens CellExp™ unc-5 homolog B (C. elegans), H. sapiens Rec.
• Alternative technique
  rec
• Alternative to gene target
  unc-5 homolog B (C. elegans), UNC5B and IDBG-77562 and ENSG00000107731 and 219699, protein binding, Plasma membranes, Unc5b and IDBG-154989 and ENSMUSG00000020099 and 107449, UNC5B and IDBG-629823 and ENSBTAG00000014270 and 100851524,524942

Gene info

• Identity
  HGNC:45096
• Gene
  UNC5B-AS1
• Long gene name
  UNC5B antisense RNA 1
• Synonyms
  • UASR1
• Locus
  10q22.1
• Discovery year
  2013-02-14
• Entrez gene record
  728978
• Pubmed identfication
  • 30805847
  • 31205563
• RefSeq identity
  • NR_038453
• Classification
  • Antisense RNAs
• VEGA ID
  OTTHUMG00000018423

Gene info

• Identity
  HGNC:12568
• Gene
  UNC5B
• Long gene name
  unc-5 netrin receptor B
• Synonyms gene name
  • unc5 (C.elegans homolog) b
  • unc-5 homolog B (C. elegans)
• Synonyms
  • UNC5H2
  • p53RDL1
• GenBank acession
  • AB096256
• Locus
  10q22.1
• Discovery year
  1998-12-09
• Entrez gene record
  219699
• Pubmed identfication
  • 12655055
  • 20693423
• RefSeq identity
  • NM_170744
• Classification
  • Ig-like cell adhesion molecule family
  • I-set domain containing
• VEGA ID
  OTTHUMG00000018422

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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