CID-755673

• Catalog number
  2660-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  2,3,4,5-Tetrahydro-7-hydroxy-1H-benzofuro[2,3-c]azepin-1-one
• Description
  CID-755673 is a selective small molecule inhibitor of protein kinase D (PKD) (IC₅₀s = 182, 280, 227 nM for PKD1, 2, and 3, respectively). It exhibits higher selectivity for PKD over Akt, polo-like kinase 1, CDK activating kinase, CAMKII and three different PKC isoforms (IC₅₀s range from 15 to > 50 µM). At 25 µM, CID-755673 has been shown to inhibit prostate cancer cell proliferation, cell migration, and invasion.
• CAS Number
  521937-07-5
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₂H₁₁NO₃
• Molecular Weight
  217.22
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (>20 mg/ml) or EtOH (~ 5 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A selective protein kinase D (PKD) inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  755673
• PubChem CID Link
• SMILES
  C1CC2=C(C(=O)NC1)OC3=C2C=C(C=C3)O
• InChi
  InChI=1S/C12H11NO3/c14-7-3-4-10-9(6-7)8-2-1-5-13-12(15)11(8)16-10/h3-4,6,14H,1-2,5H2,(H,13,15)
• InChi Key
  AACFPJSJOWQNBN-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  CID-755673  
• Short name
  CID-755673
• Alternative name
  CID-755673

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