RAT ANTI MOUSE TREM-1:Low Endotoxin Antibody
-
Catalog numberGEN219455
-
PricePlease ask
-
Size500ug
-
-
Also known asTREM-1
-
Other namestriggering receptor expressed on myeloid cells 1; Triggering receptor expressed on myeloid cells 1; triggering receptor expressed on myeloid cells 1; triggering receptor expressed in monocytes 1; triggering receptor expressed on myeloid cells 1; N/A
-
CategoryAntibodies
-
SubcategoryMnoclonal antibodies
-
Gene nameTREM-1
-
Gene name synonimsN/A
-
Other gene namesTrem1; Trem1; N/A; TREM-1
-
ClonalityMonoclonal
-
Immunoglobulin isotypeIgG2a
-
CloneL5-B8.2A12.3A12
-
Host organismRat (Rattus norvegicus)
-
Species reactivityMouse (Mus musculus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
-
Specificity and cross reactivityTREM-1 This item recognises mouse triggering receptor expressed on myeloid cells 1 (TREM-1), a 30kD member of the immunoglobulin superfamily expressed on neutrophils and a subset of monocytes. TREM-1 is involved in the microbial inflammatory response. It acts in conjunction with the adaptor protein DAP12 to activate neutrophils and monocytes, leading to the secretion of pro-inflammatory mediators and enhancement of the inflammatory response. Microbial infection also induces the release of soluble form of TREM-1 from monocytes, which is reported to act as an inhibitor of TREM-1. _x000D__x000D_TREM-1 mediates the septic shock pathway, and blocking TREM-1 has been reported to reduce inflammation and increase survival in certain models of bacterial infection. ; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
-
Purification methodN/A
-
Form AppearanceLow Endotoxin (Purified IgG - liquid)
-
ConcentrationIgG concentration 1.0mg/ml
-
Storage and shippingStore the antibody should be stored at -20 degrees Celsius. only. Storage in frost-free freezers is not recommended. the antibody should be stored undiluted. Repeated freeze - thaw cycles may denature the peptide chains of the antibody and therefore should be maximally avoided. If there is a precipitate in the vial we recommend you to briefly microcentrifugate it prior to use. Shelf Life: 18 months from date of dispatch.
-
Tested applicationsWestern Blot (WB), Immunofluorescence (IF), Functional Assay (FA), Flow Cytometry (FACS), Immunohistology - Frozen (IHC)
-
DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. This is against a protein of mus musculus directed antibody.
-
PropertiesIf you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
TestMouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
-
Latin nameMus musculus, Rattus norvegicus
-
AboutRats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
-
French translationanticorps
-
Gene target
-
Gene symbolTREM1, TREM2, IGHVII-1-1, MIR1-1, TRUND-NNN8-1, TRUND-NNN7-1, IGKV1OR2-1, MIR1289-1, MIR101-1, MIR16-1
-
Short nameANTI MOUSE TREM-1: Endotoxin Antibody
-
Techniqueanti mouse, Antibody, Mouse, anti, antibody to, anti mouse antibodies, antibodies against human proteins, antibodies for, mouses
-
HostRat
-
SpeciesMouse, Mouses, Rats
-
Alternative nameAnti-RAT ANTI MOUSE TREM-1:Low Endotoxin
-
Alternative techniqueantibodies, murine
-
Gene info
-
Identity
-
Gene
-
Long gene nametriggering receptor expressed on myeloid cells 1
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2002-08-09
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- V-set domain containing
- CD molecules
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene nametriggering receptor expressed on myeloid cells 2
-
Synonyms gene name
- triggering receptor expressed on myeloid cells 2a
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2002-08-09
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- V-set domain containing
-
VEGA ID
-
Locus Specific Databases
Gene info
-
Identity
-
Gene
-
Long gene nameimmunoglobulin heavy variable (II)-1-1 (pseudogene)
-
Synonyms gene name
- immunoglobulin heavy variable (II)-1-1
- immunoglobulin heavy variable (II)-1-1 pseudogene
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2000-04-17
-
Entrez gene record
-
RefSeq identity
-
Classification
- Immunoglobulin heavy locus at 14q32.33
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namemicroRNA 1-1
-
Synonyms gene
-
Synonyms
-
Locus
-
Discovery year2004-04-23
-
Entrez gene record
-
RefSeq identity
-
Classification
- MicroRNA MIR1/206 family
Gene info
-
Identity
-
Gene
-
Long gene nametRNA-undetermined (NNN) 8-1
-
Synonyms gene name
- transfer RNA-undetermined (NNN) 8-1
-
GenBank acession
-
Locus
-
Discovery year2014-06-20
-
Entrez gene record
-
Pubmed identfication
Gene info
-
Identity
-
Gene
-
Long gene nametRNA-undetermined (NNN) 7-1
-
Synonyms gene name
- transfer RNA-undetermined (NNN) 7-1
-
GenBank acession
-
Locus
-
Discovery year2014-06-20
-
Entrez gene record
-
Pubmed identfication
Gene info
-
Identity
-
Gene
-
Long gene nameimmunoglobulin kappa variable 1/OR2-1 (pseudogene)
-
Synonyms gene
-
Synonyms gene name
- immunoglobulin kappa variable 1/OR-1
- immunoglobulin kappa variable 1/OR-1 pseudogene
- immunoglobulin kappa variable 1/OR-1 (pseudogene)
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2000-04-18
-
Entrez gene record
-
Pubmed identfication
-
Classification
- Immunoglobulin kappa (IGK) orphons
-
VEGA ID
Gene info
-
Identity
-
Gene
-
Long gene namemicroRNA 1289-1
-
Synonyms gene
-
Synonyms
-
Locus
-
Discovery year2008-11-03
-
Entrez gene record
-
RefSeq identity
-
Classification
- MicroRNA MIR1289 family
Gene info
-
Identity
-
Gene
-
Long gene namemicroRNA 101-1
-
Synonyms gene
-
Synonyms
-
Locus
-
Discovery year2004-04-23
-
Entrez gene record
-
RefSeq identity
-
Classification
- MicroRNA MIR101 family
Gene info
-
Identity
-
Gene
-
Long gene namemicroRNA 16-1
-
Synonyms gene
-
Synonyms
-
Locus
-
Discovery year2004-04-23
-
Entrez gene record
-
RefSeq identity
-
Classification
- MicroRNA MIR15/16 family
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data