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GIT1 Ser375 Antibody ALEXA FLUOR

GIT1 Ser375 Antibody ALEXA FLUOR is available 5 times from Bioss primary conjugated antibodies. alexa fluor labs

bs-5372R-A350 | GIT1(Ser375) Antibody, ALEXA FLUOR 350 size: 100ul | 408.10 USD

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bs-5372R-A488 | GIT1(Ser375) Antibody, ALEXA FLUOR 488 size: 100ul | 408.10 USD

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bs-5372R-A555 | GIT1(Ser375) Antibody, ALEXA FLUOR 555 size: 100ul | 408.10 USD

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bs-5372R-A594 | GIT1(Ser375) Antibody, ALEXA FLUOR 594 size: 100ul | 408.10 USD

Catalog number bs-5372R-A594
Price 408.10 USD
Size 100ul
Long name GIT1(Ser375) Polyclonal Antibody, ALEXA FLUOR 594 Conjugated
Also known as Anti-GIT1 Ser375 PAb ALEXA FLUOR 594
Conjugated with ALEXA FLUOR® 594
Excitation emission 590nm/617nm
Properties For facs or microscopy Alexa 1 conjugate.If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Conjugation Alexa Fluor,ALEXA FLUOR® 594
Conjugated Alexa conjugate 1
French translation anticorps
Label ALEXA FLUOR 594
Alternative name GIT1(Ser375) Polyclonal Antibody, ALEXA FLUOR 594
1. Gene info
Identity 4272
Gene GIT1
Long gene name GIT ArfGAP 1
Synonyms gene name
  • G protein-coupled receptor kinase interactor 1
  • G protein-coupled receptor kinase interacting ArfGAP 1
GenBank acession
  • AF124490
Locus 17q11.2
Discovery year 2000-07-31
Entrez gene record 28964
Pubmed identfication
  • 9826657
  • 10896954
RefSeq identity
  • NM_014030
Classification
  • ArfGAPs
  • Ankyrin repeat domain containing
Havana BLAST/BLAT OTTHUMG00000132730
Product images
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Product files

bs-5372R-A647 | GIT1(Ser375) Antibody, ALEXA FLUOR 647 size: 100ul | 408.10 USD

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Category Conjugated Primary Antibodies
Host Organism Rabbit (Oryctolagus cuniculus)
Target Antigen GIT1 Ser375
Specificity This is a highly specific antibody against GIT1 Ser375.
Modification Phosphorylation
Modification Site Ser375
Clonality Polyclonal
Clone Polyclonal antibody
Concentration 1ug per 1ul
Source KLH conjugated synthetic phosphopeptide derived from human GIT1 around the phosphorylation site of Ser375
Gene ID Number 28964
Tested applications IF(IHC-P)
Recommended dilutions IF(IHC-P)(1:50-200)
Crossreactivity Human
Cross-reactive species details Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Background of the antigen Heterotrimeric G protein-mediated signal transduction is a dynamically regulated process with the intensity of signal decreasing over time despite the continued presence of the agonist (1,2). G protein-coupled receptor kinases (GRKs) are activated by activated G protein-coupled receptors, and they function to phosphorylate and inactivate cell surface receptors in the heterotrimeric G protein signaling cascade (3,4). GIT1 (for GRK-interactor 1) and GIT2 are GTPase-activating proteins (GAP) for members of the ADP ribosylation factor (ARF) family of small GTP-binding proteins, which are involved in vesicular trafficking (5,6). GIT1 overexpression results in reduced internalization and resensitization of b2-adrenergic receptor, thus reducing b2-adrenergic receptor signaling (5).
Purification Purified by Protein A.
Storage conditions Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
Synonyms GIT1 phospho S375; p-GIT1 S375; ARF GAP GIT1; ARF GTPase activating protein GIT1; CAT 1; Cat1; Cool associated and tyrosine phosphorylated protein 1; G protein coupled receptor kinase interactor 1; GRK interacting protein 1.
Gene targetGIT1(Ser375
Short name Anti-GIT1 Ser375
Technique Antibody
Isotype Immunoglobulin G (IgG)
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Anti-GIT1 Ser375 | Technique alternative | 01011177118
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  • GIT1(Ser375
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