CH5424802

• Catalog number
  2867-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  9-Ethyl-6,6-dimethyl-8-(4-morpholinopiperidin-1-yl)-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile; Alectinib; AF-802
• Description
  CH5424802 is a potent, selective, ATP-competitive inhibitor of anaplastic lymphoma kinase (ALK) (IC₅₀ = 1.9 nM). It displays potent antitumor activity against RET-rearranged non-small cell lung cancer (NSCLC).
• CAS Number
  1256580-46-7
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₃₀H₃₄N₄O₂
• Molecular Weight
  482.62
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (2 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A potent, selective, ATP-competitive ALK inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  49806720
• PubChem CID Link
• SMILES
  CCC1=C(C=C2C(=C1)C(=O)C3=C(C2(C)C)NC4=C3C=CC(=C4)C#N)N5CCC(CC5)N6CCOCC6
• InChi
  InChI=1S/C30H34N4O2/c1-4-20-16-23-24(17-26(20)34-9-7-21(8-10-34)33-11-13-36-14-12-33)30(2,3)29-27(28(23)35)22-6-5-19(18-31)15-25(22)32-29/h5-6,15-17,21,32H,4,7-14H2,1-3H3
• InChi Key
  KDGFLJKFZUIJMX-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  CH5424802  
• Short name
  CH5424802
• Alternative name
  CH5424802

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