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Alternative_name
4-(2-Chlorophenoxy)-N-(3-(3-methylcarbamoyl)phenyl)piperidine-1-carboxamide
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Description
Cell-permeable. A potent and selective inhibitor of SCD1(stearoyl-CoA desaturase 1) (In vitro: IC₅₀ = 37 nM for hSCD1,
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Structure Available
Yes
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Salt Form
No
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Molecular Formula
C₂₀H₂₂ClN₃O₃
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Molecular Weight
387.86
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Cell Permeable
Yes
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Purity
≥95% by HPLC
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Solubilities
DMSO (~ 180 mg/ml)
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Handling
Protect from air and light
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Tag Line
A SCD1(stearoyl-CoA desaturase 1 inhibitor
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Storage Condition
-20°C
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Shipping Condition
gel pack
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Shelf Life
24 months
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PubChem CID
24905400
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SMILES
CNC(=O)C1=CC(=CC=C1)NC(=O)N2CCC(CC2)OC3=CC=CC=C3Cl
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InChi
InChI=1S/C20H22ClN3O3/c1-22-19(25)14-5-4-6-15(13-14)23-20(26)24-11-9-16 (10-12-24)27-18-8-3-2-7-17(18)21/h2-8,13,16H,9-12H2,1H3,(H,22,25)(H,23, 26)
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InChi Key
DPYTYQFYDLYWHZ-UHFFFAOYSA-N
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MSDS Available
Yes
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Additional description
Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.
