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anti EDEM2 Antibody

anti EDEM2 Antibody is available 2 times from Biovision labs

6633-30T | anti-EDEM2 Antibody size: EDEM2 Antibody | 178.63 USD

Catalog number 6633-30T
Supplier Biovision
Price 178.63 USD
Size EDEM2 Antibody
Formulation of this antibody: 30 µg (0.5 mg/ml) polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
1. Gene info
Identity 15877
Gene EDEM2
Long gene name ER degradation enhancing alpha-mannosidase like protein 2
Synonyms gene
  • C20orf49
  • C20orf31
Synonyms gene name
  • chromosome 20 open reading frame 31
  • ER degradation enhancer, mannosidase alpha-like 2
  • FLJ10783
  • bA4204.1
GenBank acession
  • AK001645
Locus 20q11.22
Discovery year 2001-06-21
Entrez gene record 55741
Pubmed identfication
  • 15537790
  • 15579471
RefSeq identity
  • NM_018217
  • Mannosidases alpha class 1
Havana BLAST/BLAT OTTHUMG00000032322
Product images
    #0#.jpegEDEM2 Antibody

6633-100 | anti-EDEM2 Antibody size: EDEM2 Antibody | 424.10 USD

Target of this antibody: EDEM2
Alternative names of antibody target: ER degradation-enhancing alpha-mannosidase-like protein 2
Background information: Proteins expressed in the endoplasmic reticulum (ER) are tightly regulated by a variety of quality control mechanisms. Terminally misfolded proteins in the ER are retrotranslocated to the cytoplasm and degraded by proteasomes through a mechanism known as ER-associated degradation (ERAD). EDEM2 (ER degradation-enhancing alpha-mannosidase-like 2) is a 578 amino acid secreted protein that, in conjunction with other EDEM proteins (namely EDEM and EDEM3), is involved in the ERAD pathway of protein degradation. EDEM2, a member of the glycosyl hydrolase 47 family, contains a mannosidase homology domain, an N-terminal cleavable signal sequence and a C-terminal extension that is required for both ER retention and the proper function of EDEM2. Human EDEM2 shares 93% sequence identity with its mouse homolog, suggesting a conserved role between species. Two isoforms of EDEM2 exist due to alternative splicing events.
Antibody host: Rabbit
Clonality of antibody: Polyclonal
Isotype: Rabbit IgG
This antibody reacts with: Human, mouse, rat
Immunogene sequence: Synthetic peptide C-terminal
Concentration of antibody: 0.5 mg/ml
Form of antibody: Liquid
Purification method: Affinity purified antibody
This antibody has been succesfully tested for use in following methods: Western blot
Recommended usage: Western blot: 1:200
Storage information: Shelf time: 12 months in temp.: -20 deg.C
Shipping conditions: gel pack
How to handle this antibody: The antibody solution should be gently mixed before use.
Description This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Properties If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation anticorps
Gene targetEDEM2
Short name anti-EDEM2 Antibody
Technique Antibody, anti
Alternative name antibody to-EDEM2 (Antibody to)
Alternative technique antibodies
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anti-EDEM2 Antibody | Technique alternative | 01012193929
EU:+32-(0)1-658-90-45 US:+1-(408)780-0908 [email protected]
  • EDEM2
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