Xestospongin C

• Catalog number
  2621-50
• Price
  Please ask
• Size
  50 ug

• Alternative_name
  (1R,4aR,11R,12aS,13S,16aS,23R,24aS)-Eicosahydro-5H,17H-1,23:11,13-diethano-2H,14H-[1,11]dioxacycloeicosino[2,3-b:12,13-b']dipyridine; XeC; Araguspongine E
• Description
  Xestospongin C is a marine natural product isolated from Pacific basin sponges; it antagonizes the calcium-releasing action of inositol-1,4,5-trisphosphate (IP3) at the receptor level. Xestospongin C blocks the increase in intracellular calcium in vascular smooth muscle cells completely at a concentration of 25 µM. Xe C also inhibits the sarcoplasmic reticulum Ca²⁺- ATPase pump at concentrations of 700 nM.
• CAS Number
  88903-69-9
• Structure Available
  Y
• Salt Form
  No
• Molecular Formula
  C₂₈H₅₀N₂O₂
• Molecular Weight
  446.71
• Cell Permeable
  Yes
• Purity
  >90%
• Solubilities
  DMSO (~ 2 mM) or EtOH (~ 2 mM)
• Handling
  Protect from air and light
• Tag Line
  An inhibitor of IP3-mediated Ca²⁺ release
• Storage Condition
  -20 ̊C
• Shipping Condition
  Gel pack
• Shelf Life
  36 months
• MDL Number
  MFCD01862629
• PubChem CID
  9846431
• PubChem CID Link
• SMILES
  C1CCCC2CCN3CCCC(C3O2)CCCCCCC4CCN5CCCC(C5O4)CC1
• InChi
  InChI=1S/C28H50N2O2/c1-3-7-15-25-17-21-30-20-10-14-24(28(30)31-25)12-6-2-4-8-16-26-18-22-29-19-9-13-23(11-5-1)27(29)32-26/h23-28H,1-22H2/t23-,24+,25-,26-,27+,28+/m1/s1
• InChi Key
  PQYOPBRFUUEHRC-HCKQMYSWSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Xestospongin  
• Short name
  Xestospongin C
• Alternative name
  Xestospongin C

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