LY2228820

• Catalog number
  B1702-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  LY2228820; LY 2228820; LY-2228820; LY2228820 dimesylate; Ralimetinib dimesylate; 5-(2-(tert-butyl)-4-(4-fluorophenyl)-1H-imidazol-5-yl)-3-neopentyl-3H-imidazo[4,5-b]pyridin-2-amine dimethanesulfonate; 5-[2-tert-butyl-4-(4-fluorophenyl)-1H-imidazol-5-yl]-3-(2,2-dimethylpropyl)imidazo[4,5-b]pyridin-2-amine;methanesulfonic acid
• Description
  LY2228820 is a novel and potent inhibitor of p38 MAPK with IC50 of 7 nM in a cell-free assay, but does not alter p38 MAPK activation.
• CAS Number
  862507-23-1
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₆H₃₇FN₆O₆S₂
• Molecular Weight
  612.74
• Cell Permeable
  Yes
• Purity
  >98%
• Solubilities
  DMSO
• Handling
  Protect from air and light
• Tag Line
  A novel and potent inhibitor of p38 MAPK
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• MDL Number
  MFCD28101032
• PubChem CID
  11570805
• PubChem CID Link
• SMILES
  CC(C)(C)CN1C2=C(C=CC(=N2)C3=C(N=C(N3)C(C)(C)C)C4=CC=C(C=C4)F)N=C1N.CS(=O)(=O)O.CS(=O)(=O)O
• InChi
  InChI=1S/C24H29FN6.2CH4O3S/c1-23(2,3)13-31-20-17(28-22(31)26)12-11-16(27-20)19-18(14-7-9-15(25)10-8-14)29-21(30-19)24(4,5)6;2*1-5(2,3)4/h7-12H,13H2,1-6H3,(H2,26,28)(H,29,30);2*1H3,(H,2,3,4)
• InChi Key
  NARMJPIBAXVUIE-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  LY2228820  
• Short name
  LY2228820
• Alternative name
  LY2228820

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