EAI-045

• Catalog number
  B1274-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  2-(5-fluoro-2-hydroxyphenyl)-2-(3-oxo-1H-isoindol-2-yl)-N-(1,3-thiazol-2-yl)acetamide
• Description
  EAI-045 is a potent and selective EGFR inhibitor. EAI-045 targets selected drug-resistant EGFR mutants but spares the wild-type receptor. EAI-045 inhibits L858R/T790M-mutant EGFR with low-nanomolar potency in biochemical assays.
• CAS Number
  1942114-09-1
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₉H₁₄FN₃O₃S
• Molecular Weight
  383.4
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO
• Handling
  Protect from air and light
• Tag Line
  A potent and selective EGFR inhibitor.
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  121231412
• PubChem CID Link
• SMILES
  C1C2=CC=CC=C2C(=O)N1C(C3=C(C=CC(=C3)F)O)C(=O)NC4=NC=CS4
• InChi
  InChI=1S/C19H14FN3O3S/c20-12-5-6-15(24)14(9-12)16(17(25)22-19-21-7-8-27-19)23-10-11-3-1-2-4-13(11)18(23)26/h1-9,16,24H,10H2,(H,21,22,25)
• InChi Key
  YTUFHOKUFOQRDF-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  EAI-045  
• Short name
  EAI-045
• Alternative name
  EAI-045

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