Salubrinal

• Catalog number
  1980-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  N-(2,2,2-trichloro-1-(3-quinolin-8-lthioureido)ethyl)cinnamamide; SAL; eIF-2α Inhibitor
• Description
  Cell-permeable. A selective inhibitor of cellular phosphatase complexes that dephosphorylate eukaryotic translation initiation factor 2 subunit α (eIF-2α). Also protects cells from endoplasmic reticulum stress-induced apoptosis (EC₅₀ ~ 15 μM).
• CAS Number
  405060-95-9
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₁H₁₇Cl₃N₄OS
• Molecular Weight
  479.81
• Cell Permeable
  Yes
• Purity
  ≥90% by HPLC
• Solubilities
  DMSO ( 100 mM)
• Handling
  Protect from light and mositure
• Tag Line
  A selective eIF-2α inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  60 months
• MDL Number
  MFCD00548612
• PubChem CID
  5717801
• PubChem CID Link
• SMILES
  C1=CC=C(C=C1)C=CC(=O)NC(C(Cl)(Cl)Cl)NC(=S)NC2=CC=CC3=C2N=CC=C3
• InChi
  InChI=1S/C21H17Cl3N4OS/c22-21(23,24)19(27-17(29)12-11-14-6-2-1-3-7-14)28-20(30)26-16-10-4-8-15-9-5-13-25-18(15)16/h1-13,19H,(H,27,29)(H2,26,28,30)/b12-11+
• InChi Key
  LCOIAYJMPKXARU-VAWYXSNFSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Salubrinal  
• Short name
  Salubrinal
• Alternative name
  Salubrinal

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