PP2

Alternative_name

1-tert-Butyl-3-(4-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine
Description

An inhibitor of the Src family of kinases. Inhibits Src and Lck kinase with IC₅₀ values of 36 nM and 31 nM respectively. Also shown to inhibit RIP2( IC₅₀ = 19 nM) and CK1δ (IC₅₀ = 41 nM).
CAS Number

172889-27-9
Structure Available

Yes
Salt Form

No
Molecular Formula

C₁₅H₁₆ClN₅
Molecular Weight

301.78
Cell Permeable

Yes
Purity

≥98% by HPLC
Solubilities

DMSO (25 mM) and EtOH (10 mM)
Handling

Protect from air and light
Tag Line

An inhibitor of the Src family of kinases
Storage Condition

-20°C
Shipping Condition

gel pack
Shelf Life

24 months
MDL Number

MFCD01568210
PubChem CID

4878
PubChem CID Link
SMILES

CC(C)(C)N1C2=C(C(=N1)C3=CC=C(C=C3)Cl)C(=NC=N2)N
InChi

InChI=1S/C15H16ClN5/c1-15(2,3)21-14-11(13(17)18-8-19-14)12(20-21)9-4-6-10(16)7-5-9/h4-8H,1-3H3,(H2,17,18,19)
InChi Key

PBBRWFOVCUAONR-UHFFFAOYSA-N
Data Sheet Link
MSDS Available

Yes