MDC Antibody

• Catalog number
  5531-100
• Price
  Please ask
• Size
  100 µg

• Antibody Target
  MDC
• Target Alternative Name
  Macrophage-derived chemokine, C-C motif chemokine 22, Stimulated T-cell chemotactic protein 1, CC chemokine STCP-1
• Antibody Type
  Polyclonal
• Species Reactivities
  Mouse, rat
• Immunogen Sequence
  E. coli-expressed mouse MDC
• Accession
  AAD50547
• Gene Id
  5757694
• Appearance
  Colorless liquid
• Form
  Liquid
• Concentration
  0.5 mg/ml
• Formulation
  100 µg (0.5 mg/ml) affinity purified rabbit anti-mouse MDC polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, 1% BSA, 0.02% thimerosal.
• Purification
  Affinity purified
• Application
  Western blot
• Application And Usages
  Western blot analysis (0.5-4 µg/ml). However, the optimal conditions should be determined individually. Rat spleen tissue lysate can be used as a positive control.
• Description
  MDC (macrophage-derived chemokine) is a 69-amino acid CC chemokine with a N-terminal sequence of 24 residues as a signal sequence. It was originally cloned from human monocyte-derived macrophages. Recombinant MDC attracts monocyte-derived dendritic cells, activated lymphocytes and natural killer cells. MDC has anti-HIV-1 activity. Expression of MDC mRNA in macrophages is enhanced by LPS, IL-1β and TNFα. MDC is a functional ligand for CCR4.
• Storage Condition
  -20 °C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• Usage
  For Research Use Only! Not to be used in humans.
• Handling
  The antibody solution should be gently mixed before use.
• Western Blot Verified
  Verified
• Immunocytochemistry Verified
  Not Verified
• Immunofluorescence Verified
  Not Verified
• Immunoprecipitation Verified
  Not Verified
• FACS Verified
  Not Verified
• ELISA Verified
  Not Verified
• ChIP Verified
  Not Verified
• Flow Cytometry Verified
  Not Verified
• Data Sheet Link
• Properties
  If you buy Antibodies supplied by Biovision they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  MDC  
• Gene symbol
  ADAM11, ADAM28, TNFAIP8, CCL22
• Short name
  MDC Antibody
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  MDC (antibody to-)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:189
• Gene
  ADAM11
• Long gene name
  ADAM metallopeptidase domain 11
• Synonyms gene
  • MDC
• Synonyms gene name
  • a disintegrin and metalloproteinase domain 11
• Synonyms name
  • metalloproteinase-like, disintegrin-like, cysteine-rich protein
• GenBank acession
  • D17390
• Locus
  17q21.31
• Discovery year
  1993-11-01
• Entrez gene record
  4185
• Pubmed identfication
  • 8252040
• RefSeq identity
  • NM_002390
• Classification
  • ADAM metallopeptidase domain containing
• VEGA ID
  OTTHUMG00000179038

Gene info

• Identity
  HGNC:206
• Gene
  ADAM28
• Long gene name
  ADAM metallopeptidase domain 28
• Synonyms gene name
  • a disintegrin and metalloproteinase domain 28
• Synonyms
  • eMDCII
  • MDC-Lm
  • MDC-Ls
  • ADAM23
• GenBank acession
  • AJ242015
• Locus
  8p21.2
• Discovery year
  1999-07-29
• Entrez gene record
  10863
• Pubmed identfication
  • 10794709
  • 15013428
• RefSeq identity
  • NM_021778
• Classification
  • ADAM metallopeptidase domain containing
• VEGA ID
  OTTHUMG00000163780

Gene info

• Identity
  HGNC:17260
• Gene
  TNFAIP8
• Long gene name
  TNF alpha induced protein 8
• Synonyms gene name
  • tumor necrosis factor, alpha-induced protein 8
• Synonyms
  • GG2-1
  • MDC-3.13
  • SCC-S2
• GenBank acession
  • AF070671
• Locus
  5q23.1
• Discovery year
  2004-02-11
• Entrez gene record
  25816
• Pubmed identfication
  • 10233894
  • 10644768
• RefSeq identity
  • NM_014350
• VEGA ID
  OTTHUMG00000162949

Gene info

• Identity
  HGNC:10621
• Gene
  CCL22
• Long gene name
  C-C motif chemokine ligand 22
• Synonyms gene
  • SCYA22
• Synonyms gene name
  • small inducible cytokine subfamily A (Cys-Cys), member 22
  • chemokine (C-C motif) ligand 22
• Synonyms
  • MDC
  • STCP-1
  • ABCD-1
  • DC/B-CK
  • A-152E5.1
  • MGC34554
• GenBank acession
  • U83171
• Locus
  16q21
• Discovery year
  1997-08-22
• Entrez gene record
  6367
• Pubmed identfication
  • 9151897
  • 9691168
• RefSeq identity
  • NM_002990
• Classification
  • Chemokine ligands
• VEGA ID
  OTTHUMG00000133454

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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