LY2811376
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Catalog numberB1606-25
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PricePlease ask
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Size25 mg
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Alternative_nameLY 2811376, LY-2811376, BACE-1 Inhibitor, (4S)-4-(2,4-difluoro-5-pyrimidin-5-ylphenyl)-4-methyl-5,6-dihydro-1,3-thiazin-2-amine
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DescriptionLY2811376 is a BACE1 inhibitor with marked Ab-lowering effects in animal models.
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CAS Number1194044-20-6
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₁₅H₁₄F₂N₄S
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Molecular Weight320.36
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Cell PermeableYes
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Purity99.88% by LCMS
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SolubilitiesDMSO: >31 mg/ml
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HandlingProtect from air and light
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Tag LineA BACE1 inhibitor with marked Ab-lowering effects in animal models.
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life36 months
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MDL NumberMFCD18074525
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PubChem CID44251605
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SMILESCC1(CCSC(=N1)N)C2=C(C=C(C(=C2)C3=CN=CN=C3)F)F
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InChi1S/C15H14F2N4S/c1-15(2-3-22-14(18)21-15)11-4-10(12(16)5-13(11)17)9-6-19-8-20-7-9/h4-8H,2-3H2,1H3,(H2,18,21)/t15-/m0/s1
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InChi KeyMJQMRGWYPNIERM-HNNXBMFYSA-N
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MSDS AvailableYes
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Gene target
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Short nameLY2811376
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Alternative nameLY2811376
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