Mouse anti Fibronectin

• Catalog number
  X1263M
• Price
  Please ask
• Size
  100 μg

• Category
  Primary Antibodies
• Long description
  Fibronectins are a family of plasma and extracellular matrix glycoproteins that contain multiple sites for various ligands and cells. The region of fibronectin that mediates cell adhesion in a majority of cell types is in the carboxy terminal domain and involves the binding of the Arg-Gly-Asp (RGD) sequence to a specific polypeptide cell surface receptor. Although the mechanisms of fibronectin extracellular matrix assembly are not well understood, specific antibodies have been used to determine the domains involved in matrix assembly._x000B__x000B_This antibody stains the extracellular adhesive glycoprotein of fibronectin in connective tissues and vessels. It does not recognize the soluble dimeric form of fibronectin (plasma fibronectin) but strongly stains matrix fibronectin in tissues. Animal biodistribution experiments have shown that after intravenous administration, this antibody localizes to tumor vessels where it binds to the underlying basement membrane. The antigen is not accessible in normal tissues to circulating antibody indicating that this antibody can be used to target tumor vessels specifically in vivo.
• Antibody come from
  n/a
• Other description
  Provided in solution at 1 mg/ml in phosphate buffered saline. Protein A/G Chromatography
• Clone
  EP5
• Antigen antibody binding interaction
  Mouse anti Fibronectin Antibody
• Antibody is raised in
  Mouse
• Antibody s reacts with
  Human, Mouse
• Antibody s reacts with these species
  This antibody doesn't cross react with other species
• Antibody s specificity
  No Data Available
• Application
  Immunohistochemistry (frozen and paraffin)
• Antibody s suited for
  For use with EDG6 (S1P4) (CT) polyclonal antibody (Cat. No. X1182P).
• Storage
  -20ºC
• Relevant references
  no information yet
• Protein number
  see ncbi
• Warnings
  This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
• Antibody s link
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus

• Gene target
  Fibronectin  
• Gene symbol
  FANK1, FNDC3A, FLRT3
• Short name
  Mouse anti Fibronectin
• Technique
  Mouse, anti, antibody to, mouses
• Host
  mouse
• Isotype
  IgG1
• Label
  unlabeled
• Species
  Mouse, Mouses
• Alternative name
  Mouse antibody to Fibronectin
• Alternative technique
  murine, antibodies

Gene info

• Identity
  HGNC:23527
• Gene
  FANK1
• Long gene name
  fibronectin type III and ankyrin repeat domains 1
• Synonyms gene name
  • fibronectin type 3 and ankyrin repeat domains 1
• GenBank acession
  • BC024189
• Locus
  10q26.2
• Discovery year
  2003-11-21
• Entrez gene record
  92565
• Pubmed identfication
  • 17604233
• RefSeq identity
  • NM_145235
• Classification
  • Ankyrin repeat domain containing
  • Fibronectin type III domain containing
• VEGA ID
  OTTHUMG00000019241

Gene info

• Identity
  HGNC:20296
• Gene
  FNDC3A
• Long gene name
  fibronectin type III domain containing 3A
• Synonyms gene
  • FNDC3
• Synonyms gene name
  • fibronectin type III domain containing 3
• Synonyms
  • bA203I16.5
  • KIAA0970
• GenBank acession
  • AB023187
• Locus
  13q14.2
• Discovery year
  2004-04-16
• Entrez gene record
  22862
• RefSeq identity
  • NM_014923
• Classification
  • Fibronectin type III domain containing
• VEGA ID
  OTTHUMG00000016911

Gene info

• Identity
  HGNC:3762
• Gene
  FLRT3
• Long gene name
  fibronectin leucine rich transmembrane protein 3
• GenBank acession
  • AF169677
• Locus
  20p12.1
• Discovery year
  1999-10-29
• Entrez gene record
  23767
• Pubmed identfication
  • 10644439
• RefSeq identity
  • NM_013281
• Classification
  • Fibronectin type III domain containing
• VEGA ID
  OTTHUMG00000031914

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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