Anti-MCP-3/CCL7 (Polyclonal), ALEXA Fluor 594

• Catalog number
  GENTObs-1986R-A594
• Price
  Please ask
• Size
  100 microliters

• Type
  Conjugated Primary Antibody
• Conjugated with
  ALEXA FLUOR® 594
• Host organism
  Rabbit (Oryctolagus cuniculus)
• Target Protein Peptide
  MCP-3/CCL7
• Specificity
  Due to the homology of this protein to related protein CCL2, there is a chance that this antibody will have a secondary cross-reaction with this the protein as well, based upon an 81% non-contiguous sequence similarity.MCP-3/CCL7
• Modification
  No modification has been applied to this antibody
• Modification site
  None
• Clonality
  Polyclonal Antibody
• Clone
  Polyclonal Antibodies
• Concentration
  1ug per 1ul
• Subcellular locations
  Secreted
• Antigen Source
  KLH conjugated synthetic peptide derived from human MCP-3
• Gene ID
  6354
• Swiss Prot
  P80098
• Applications
  IF(IHC-P)
• Applications with corresponding dilutions
  IF(IHC-P)(1:50-200)
• Cross reactive species
  Human (Homo sapiens)
• Cross Reactive Species details
  No significant cross reactivity has been observed for this antibody for the tested species. However, note that due to limited knowledge it is impossible to predict with 100% guarantee that the antibody does not corss react with any other species.
• Background information
  Chemotactic factor that attracts monocytes and eosinophils, but not neutrophils. Augments monocyte anti-tumor activity. Also induces the release of gelatinase B. This protein can bind heparin. Binds to CCR1, CCR2 and CCR3.
• Purification method
  Purified by Protein A.
• Storage
  Water buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide. Store at 4°C for 12 months.
• Excitation emission
  590nm/617nm
• Synonyms
  FIC; MARC; MCP3; NC28; MCP-3; SCYA6; SCYA7; C-C motif chemokine 7; Monocyte chemoattractant protein 3; Monocyte chemotactic protein 3; Small-inducible cytokine A7; CCL7
• Also known as
  MCP-3/CCL7 Polyclonal Antibody
• Other name
  Anti-MCP-3/CCL7 Polyclonal
• Advisory
  Avoid freeze/thaw cycles as they may denaturate the polypeptide chains of the antibody, thus reducing its reactivity, specificity and sensitivity. For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube. Prior to use briefly centrifuge the vial to gather all the solution on the bottom.
• Properties
  For facs or microscopy Alexa 1 conjugate.
• Conjugation
  Alexa Fluor, ALEXA FLUOR® 594
• Conjugated
  Alexa conjugate 1
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Group
  Polyclonals and antibodies
• About
  Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.

• Gene target
  MCP-3/CCL7  
• Gene symbol
  CCL7, CAPG, CCL8, SLC25A33, CD46, MIR1302-3, MIR509-3, MIR7-3, PIRC14
• Short name
  Anti-MCP-3/CCL7
• Technique
  Polyclonal, anti-, anti, antibody to, antibodies, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 594
• Alternative name
  MCP-3/CCL7 Polyclonal Antibody, ALEXA FLUOR® 594 Conjugated
• Alternative technique
  polyclonals, antibodies
• Alternative to gene target
  chemokine (C-C motif) ligand 7, FIC and MARC and MCP-3 and MCP3 and NC28 and SCYA6 and SCYA7, CCL7 and IDBG-40580 and ENSG00000108688 and 6354, CCR2 chemokine receptor binding, Extracellular, Ccl7 and IDBG-204496 and ENSMUSG00000035373 and 20306

Gene info

• Identity
  HGNC:10634
• Gene
  CCL7
• Long gene name
  C-C motif chemokine ligand 7
• Synonyms gene
  • SCYA6
  • SCYA7
• Synonyms gene name
  • small inducible cytokine A7 (monocyte chemotactic protein 3)
  • chemokine (C-C motif) ligand 7
• Synonyms
  • MCP-3
  • NC28
  • FIC
  • MARC
  • MCP3
• Synonyms name
  • monocyte chemoattractant protein 3
  • monocyte chemotactic protein 3
• GenBank acession
  • AF043338
• Locus
  17q12
• Discovery year
  1993-11-04
• Entrez gene record
  6354
• Pubmed identfication
  • 8461011
• RefSeq identity
  • NM_006273
• Classification
  • Chemokine ligands
• VEGA ID
  OTTHUMG00000132889

Gene info

• Identity
  HGNC:1474
• Gene
  CAPG
• Long gene name
  capping actin protein, gelsolin like
• Synonyms gene
  • AFCP
• Synonyms gene name
  • capping protein (actin filament), gelsolin-like
• Synonyms
  • MCP
• Synonyms name
  • macrophage capping protein
• GenBank acession
  • M94345
• Locus
  2p11.2
• Discovery year
  1993-12-14
• Entrez gene record
  822
• Pubmed identfication
  • 1322908
  • 12754261
• RefSeq identity
  • NM_001747
• Classification
  • Gelsolin/villins
• VEGA ID
  OTTHUMG00000130183

Gene info

• Identity
  HGNC:10635
• Gene
  CCL8
• Long gene name
  C-C motif chemokine ligand 8
• Synonyms gene
  • SCYA8
• Synonyms gene name
  • small inducible cytokine subfamily A (Cys-Cys), member 8 (monocyte chemotactic protein 2)
  • chemokine (C-C motif) ligand 8
• Synonyms
  • MCP-2
  • HC14
• GenBank acession
  • X99886
• Locus
  17q12
• Discovery year
  1996-11-14
• Entrez gene record
  6355
• Pubmed identfication
  • 9119400
• RefSeq identity
  • NM_005623
• Classification
  • Chemokine ligands
• VEGA ID
  OTTHUMG00000132883

Gene info

• Identity
  HGNC:29681
• Gene
  SLC25A33
• Long gene name
  solute carrier family 25 member 33
• Synonyms gene name
  • solute carrier family 25, member 33
  • solute carrier family 25 (pyrimidine nucleotide carrier), member 33
• Synonyms
  • MGC4399
  • BMSC-MCP
  • PNC1
• GenBank acession
  • AF495714
• Locus
  1p36.22
• Discovery year
  2006-09-21
• Entrez gene record
  84275
• Pubmed identfication
  • 14715278
  • 16949250
• RefSeq identity
  • NM_032315
• Classification
  • Solute carriers
• VEGA ID
  OTTHUMG00000001322

Gene info

• Identity
  HGNC:6953
• Gene
  CD46
• Long gene name
  CD46 molecule
• Synonyms gene
  • MIC10
  • MCP
• Synonyms gene name
  • antigen identified by monoclonal antibody TRA-2-10
  • membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen)
  • CD46 antigen, complement regulatory protein
  • CD46 molecule, complement regulatory protein
• Synonyms
  • TRA2.10
  • MGC26544
  • TLX
• GenBank acession
  • BC030594
• Locus
  1q32.2
• Discovery year
  1988-08-31
• Entrez gene record
  4179
• Pubmed identfication
  • 7929741
• RefSeq identity
  • NM_172361
• Classification
  • Sushi domain containing
  • Complement system regulators and receptors
  • CD molecules
• VEGA ID
  OTTHUMG00000036397
• Locus Specific Databases
  • LRG_155

Gene info

• Identity
  HGNC:35295
• Gene
  MIR1302-3
• Long gene name
  microRNA 1302-3
• Synonyms gene
  • MIRN1302-3
• Synonyms
  • hsa-mir-1302-3
• Locus
  2q14.1
• Discovery year
  2008-11-03
• Entrez gene record
  100302128
• RefSeq identity
  • NR_031632
• Classification
  • MicroRNA MIR1302 family

Gene info

• Identity
  HGNC:33675
• Gene
  MIR509-3
• Long gene name
  microRNA 509-3
• Synonyms gene
  • MIRN509-3
• Synonyms
  • hsa-mir-509-3
• Locus
  Xq27.3
• Discovery year
  2007-10-24
• Entrez gene record
  100126337
• RefSeq identity
  • NR_030629
• Classification
  • MicroRNA MIR506 family

Gene info

• Identity
  HGNC:31640
• Gene
  MIR7-3
• Long gene name
  microRNA 7-3
• Synonyms gene
  • MIRN7-3
• Synonyms
  • hsa-mir-7-3
• Locus
  19p13.3
• Discovery year
  2004-04-23
• Entrez gene record
  407045
• RefSeq identity
  • NR_029607
• Classification
  • MicroRNA MIR7 family

Gene info

• Identity
  HGNC:37518
• Gene
  PIRC14
• Long gene name
  piwi-interacting RNA cluster 14
• Locus
  3
• Discovery year
  2009-11-05
• Entrez gene record
  100313784
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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