ATG7 Antibody

• Catalog number
  R31385
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  ATG7
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB
• Recommended dilutions
  Western blot: 0.5-1ug/ml
• Notes
  Titration of the ATG7 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This ATG7 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  O95352
• Purity
  Antigen affinity
• Description
  Autophagy-related protein 7 is a protein that in humans is encoded by the ATG7 gene. This gene was identified based on homology to Pichia pastoris GSA7 and Saccharomyces cerevisiae APG7. In the yeast, the protein appears to be required for fusion of peroxisomal and vacuolar membranes. The protein also shows homology to the ATP-binding and catalytic sites of the E1 ubiquitin activating enzymes. ATG7 is essential for the Apg12 conjugation system that mediates membrane fusion in autophagy. It is found that when nutrients are limited, the protein can regulate p53-dependent cell cycle and cell death pathways.
• Immunogen
  Amino acids 652-669 (KVLDQYEREGFNFLAKVF-human) were used as the immunogen for this ATG7 antibody.
• Storage
  After reconstitution, the ATG7 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  ATG7  
• Gene symbol
  ATG7
• Short name
  Anti-ATG7
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to ATG7
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:16935
• Gene
  ATG7
• Long gene name
  autophagy related 7
• Synonyms gene
  • APG7L
• Synonyms gene name
  • APG7 autophagy 7-like (S. cerevisiae)
  • ATG7 autophagy related 7 homolog (S. cerevisiae)
• Synonyms
  • GSA7
  • DKFZp434N0735
• Synonyms name
  • ubiquitin-activating enzyme E1-like protein
• GenBank acession
  • AF094516
• Locus
  3p25.3
• Discovery year
  2003-11-20
• Entrez gene record
  10533
• Pubmed identfication
  • 10233149
• RefSeq identity
  • NM_006395
• Classification
  • Ubiquitin like modifier activating enzymes
  • Autophagy related
• VEGA ID
  OTTHUMG00000129740

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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