Mps1-IN-1

Alternative_name

1-[3-methoxy-4-[[4-(2-propan-2-ylsulfonylanilino)-1H-pyrrolo[2,3-b]pyridin-6-yl]amino]phenyl]piperidin-4-ol, Mps 1 Inhibitor, Mps1 IN 1
Description

Mps1-IN-1 is a highly potent and selectibe Mpsl inhibitor
CAS Number

1125593-20-5
Structure Available

Yes
Salt Form

No
Molecular Formula

C₂₈H₃₃N₅O₄S
Molecular Weight

535.66
Cell Permeable

Yes
Purity

97% by HPLC
Solubilities

DMSO: ≥ 39 mg/ml
Handling

Protect from air and light
Tag Line

A highly potent and selectibe Mpsl inhibitor
Storage Condition

-20°C
Shipping Condition

gel pack
Shelf Life

36 months
MDL Number

MFCD22124489
PubChem CID

25195352
PubChem CID Link
SMILES

CC(C)S(=O)(=O)C1=CC=CC=C1NC2=CC(=NC3=C2C=CN3)NC4=C(C=C(C=C4)N5CCC(CC5)O)OC
InChi

1S/C28H33N5O4S/c1-18(2)38(35,36)26-7-5-4-6-23(26)30-24-17-27(32-28-21(24)10-13-29-28)31-22-9-8-19(16-25(22)37-3)33-14-11-20(34)12-15-33/h4-10,13,16-18,20,34H,11-12,14-15H2,1-3H3,(H3,29,30,31,32)
InChi Key

NMJMRSQTDLRCRQ-UHFFFAOYSA-N
Data Sheet Link
MSDS Available

Yes

Gene target

Mps1-IN-1
Gene symbol

CD44, IGHVII-1-1, MIR1-1, TRUND-NNN8-1, TRUND-NNN7-1, IGKV1OR2-1, MIR1289-1, MIR101-1, MIR16-1
Short name

Mps1-IN-1
Alternative name

Mps1-IN-1

Identity

HGNC:1681
Gene

CD44
Long gene name

CD44 molecule (Indian blood group)
Synonyms gene
- MIC4
- MDU2
- MDU3
Synonyms gene name
- CD44 antigen (homing function and Indian blood group system)
Synonyms
- IN
- MC56
- Pgp1
- CD44R
- HCELL
- CSPG8
Synonyms name
- hematopoietic cell E- and L-selectin ligand
- chondroitin sulfate proteoglycan 8
GenBank acession
- M59040
Locus

11p13
Discovery year

1989-06-30
Entrez gene record

960
Pubmed identfication
- 2454887
RefSeq identity
- NM_000610
Classification
- Proteoglycans
- Blood group antigens
- CD molecules
VEGA ID

OTTHUMG00000044388
Locus Specific Databases
- LRG_815

Identity

HGNC:5670
Gene

IGHVII-1-1
Long gene name

immunoglobulin heavy variable (II)-1-1 (pseudogene)
Synonyms gene name
- immunoglobulin heavy variable (II)-1-1
- immunoglobulin heavy variable (II)-1-1 pseudogene
Synonyms
- IGHV(II)-1-1
GenBank acession
- AB019441
Locus

14q32.33
Discovery year

2000-04-17
Entrez gene record

28377
RefSeq identity
- NG_001019
Classification
- Immunoglobulin heavy locus at 14q32.33
VEGA ID

OTTHUMG00000152325

Identity

HGNC:5760
Gene

IGKV1OR2-1
Long gene name

immunoglobulin kappa variable 1/OR2-1 (pseudogene)
Synonyms gene
- IGKVPZ1
- IGKV1OR-1
Synonyms gene name
- immunoglobulin kappa variable 1/OR-1
- immunoglobulin kappa variable 1/OR-1 pseudogene
- immunoglobulin kappa variable 1/OR-1 (pseudogene)
Synonyms
- IGKV1/OR-1
- IGKV1/OR2-1
GenBank acession
- Z12367
Locus

2p11.1
Discovery year

2000-04-18
Entrez gene record

3531
Pubmed identfication
- 2853098
Classification
- Immunoglobulin kappa (IGK) orphons
VEGA ID

OTTHUMG00000155081