Cobimetinib
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Catalog numberB1689-5
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PricePlease ask
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Size5 mg
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Alternative_nameCobimetinib; XL518; XL-518; XL 518; GDC0973; GD C0973; GDC-0973; [3,4-difluoro-2-(2-fluoro-4-iodoanilino)phenyl]-[3-hydroxy-3-[(2S)-piperidin-2-yl]azetidin-1-yl]methanone
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DescriptionCobimetinib(GDC-0973; XL518) is a potent, highly selective inhibitor of mitogen-activated protein kinase kinase(MEK1/2).
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CAS Number934660-93-2
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₂₁H₂₁F₃IN₃O₂
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Molecular Weight531.31
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Cell PermeableYes
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Purity>98%
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SolubilitiesDMSO
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HandlingProtect from air and light
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Tag LineA selective MEK inhibitor
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life36 months
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MDL NumberNA
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PubChem CID16222096
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SMILESC1CCNC(C1)C2(CN(C2)C(=O)C3=C(C(=C(C=C3)F)F)NC4=C(C=C(C=C4)I)F)O
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InChiInChI=1S/C21H21F3IN3O2/c22-14-6-5-13(19(18(14)24)27-16-7-4-12(25)9-15(16)23)20(29)28-10-21(30,11-28)17-3-1-2-8-26-17/h4-7,9,17,26-27,30H,1-3,8,10-11H2/t17-/m0/s1
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InChi KeyBSMCAPRUBJMWDF-KRWDZBQOSA-N
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MSDS AvailableYes
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Gene target
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Short nameCobimetinib
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Alternative nameCobimetinib
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