Cobimetinib

  • Catalog number
    B1689-5
  • Price
    Please ask
  • Size
    5 mg
  • Alternative_name
    Cobimetinib; XL518; XL-518; XL 518; GDC0973; GD C0973; GDC-0973; [3,4-difluoro-2-(2-fluoro-4-iodoanilino)phenyl]-[3-hydroxy-3-[(2S)-piperidin-2-yl]azetidin-1-yl]methanone
  • Description
    Cobimetinib(GDC-0973; XL518) is a potent, highly selective inhibitor of mitogen-activated protein kinase kinase(MEK1/2).
  • CAS Number
    934660-93-2
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₂₁H₂₁F₃IN₃O₂
  • Molecular Weight
    531.31
  • Cell Permeable
    Yes
  • Purity
    >98%
  • Solubilities
    DMSO
  • Handling
    Protect from air and light
  • Tag Line
    A selective MEK inhibitor
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    36 months
  • MDL Number
    NA
  • PubChem CID
    16222096
  • SMILES
    C1CCNC(C1)C2(CN(C2)C(=O)C3=C(C(=C(C=C3)F)F)NC4=C(C=C(C=C4)I)F)O
  • InChi
    InChI=1S/C21H21F3IN3O2/c22-14-6-5-13(19(18(14)24)27-16-7-4-12(25)9-15(16)23)20(29)28-10-21(30,11-28)17-3-1-2-8-26-17/h4-7,9,17,26-27,30H,1-3,8,10-11H2/t17-/m0/s1
  • InChi Key
    BSMCAPRUBJMWDF-KRWDZBQOSA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    Cobimetinib
  • Alternative name
    Cobimetinib
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