Cercosporamide

• Catalog number
  9662-100
• Price
  Please ask
• Size
  100 ug

• Alternative_name
  (9aS)-8-Acetyl-9,9a-dihydro-1,3,7-trihydroxy-9a-methyl-9-oxo-4-dibenzofurancaboxamide
• Description
  Cercosporamide is a potent inhibitor of MAP-kinase interacting kinases (Mnk1 and Mnk2), and JAK3 (IC₅₀ values are 115, 11, and 31 nM for Mnk1, Mnk2 and JAK3, respectively). Also inhibits Pkc1. Blocks eIF4E phosphorylation; exhibits antiproliferative and proapoptotic activity in cancer cells in vitro.
• CAS Number
  131436-22-1
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₆H₁₃NO₇
• Molecular Weight
  331.28
• Cell Permeable
  Yes
• Purity
  ≥95%
• Solubilities
  DMSO (~ 3 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A potent inhibitor of MAP-kinase interacting kinase-2 (Mnk2) inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• PubChem CID
  10019578
• PubChem CID Link
• SMILES
  CC(=O)C1=C(C=C2C(C1=O)(C3=C(C=C(C(=C3O2)C(=O)N)O)O)C)O
• InChi
  InChI=1S/C16H13NO7/c1-5(18)10-7(20)4-9-16(2,14(10)22)12-8(21)3-6(19)11(15(17)23)13(12)24-9/h3-4,19-21H,1-2H3,(H2,17,23)
• InChi Key
  GEWLYFZWVLXQME-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  Cercosporamide  
• Short name
  Cercosporamide
• Alternative name
  Cercosporamide

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