Carbohydrate kinase domain containing; carbohydrate kinase domain-containing protein; FLJ10769; LP3298; NNRD_HUMAN.
Also known as
This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human CARKD
Human, Mouse, Rat
This is a highly specific antibody against CARKD.
CARKD Primary Polyclonal Antibody
WB, IHC-P, IF(IHC-P)
WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
Background of the target antigen
CARKD is a 347 amino acid protein that belongs to the YjeF family and exists as three alternatively spliced isoforms. Containing one YjeF C-terminal domain, CARKD is encoded by a gene that maps to human chromosome 13q34. Chromosome 13 contains around 114 million base pairs and 400 genes. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene. RB1 encodes a crucial tumor suppressor protein which, when defective, leads to malignant growth in the retina and has been implicated in a variety of other cancers. The gene SLITRK1, which is associated with Tourette syndrome, is on chromosome 13. As with most chromosomes, polysomy of part or all of chromosome 13 is deleterious to development and decreases the odds of survival. Trisomy 13, also known as Patau syndrome, is quite deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections.
1ug per 1ul
This antibody was purified via Protein A.
Cross reactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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