NSC-23925

• Catalog number
  2686-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  2-(p-Methoxyphenyl)-α-2-piperidyl-4-quinolinemethanol dihydrochloride, NSC-23925, [2-(4-Methoxyphenyl)4-quinolinyl]-(piperidin-2-y)-methanol dihydrochloride
• Description
  NSC-23925 is a potent plasma membrane glycoprotein 1(Pgp1) inhibitor. It inhibits Pgp1 and reverses MDR1 (Pgp1) but does not inhibit MRP or BCRP-mediated MDR. NSC23925 directly inhibits the function of Pgp1 in a dose-dependent manner without altering the total expression level of Pgp1. NSC23925 stimulates ATPase activity of Pgp.
• CAS Number
  858474-14-3
• Structure Available
  Y
• Salt Form
  No
• Molecular Formula
  C₂₂H₂₄N₂O₂ · 2HCl
• Molecular Weight
  421.36
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  H₂O (~5 mg/ml)
• Handling
  Protect from air and moisture
• Tag Line
  A potent plasma membrane glycoprotein 1(Pgp1) inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  Gel pack
• Shelf Life
  36 months
• MDL Number
  MFCD22666390
• PubChem CID
  54601129
• PubChem CID Link
• SMILES
  OC(C1NCCCC1)C2=CC(C3=CC=C(OC)C=C3)=NC4=CC=CC=C24.[H]Cl.[H]Cl
• InChi
  InChI=1S/C22H24N2O2.2ClH/c1-26-16-11-9-15(10-12-16)21-14-18(17-6-2-3-7-19(17)24-21)22(25)20-8-4-5-13-23-20;;/h2-3,6-7,9-12,14,20,22-23,25H,4-5,8,13H2,1H3;2*1H
• InChi Key
  WGWOQHWZXLGPNG-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  NSC-23925  
• Short name
  NSC-23925
• Alternative name
  NSC-23925

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