α-Cyano-4-hydroxycinnamic acid

• Catalog number
  B2162-1000
• Price
  Please ask
• Size
  1 g

• Alternative_name
  α-CCA; 4-HCCA; CHCA; NSC173138; 4-CIN
• Description
  α-Cyano-4-hydroxycinnamate (4-CIN) is a monocarboxylate transporter (MCT) inhibitor. Displays antitumor and antiangiogenic activity in gliomas in vivo; decreases glycolytic metabolism, migration, and invasion in U251 cells. Also blocks lactate efflux from glioma cells and sensitizes cells to irradiation.
• CAS Number
  28166-41-8
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₁₀H₇NO₃
• Molecular Weight
  189.17
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (10 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A monocarboxylate transporter (MCT) inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• MDL Number
  MFCD00004204
• PubChem CID
  5328791
• PubChem CID Link
• SMILES
  C1=CC(=CC=C1C=C(C#N)C(=O)O)O
• InChi
  InChI=1S/C10H7NO3/c11-6-8(10(13)14)5-7-1-3-9(12)4-2-7/h1-5,12H,(H,13,14)/b8-5+
• InChi Key
  AFVLVVWMAFSXCK-VMPITWQZSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  α-Cyano-4-hydroxycinnamic   acid  
• Gene symbol
  MIR1302-4, PIRC18, PIRC16, SNORD114-4, MIR941-4, IGKV2OR2-4, ANKRD20A12P, PIRC17
• Short name
  α-Cyano-4-hydroxycinnamic acid
• Alternative name
  α-Cyano-4-hydroxycinnamic acid

Gene info

• Identity
  HGNC:35296
• Gene
  MIR1302-4
• Long gene name
  microRNA 1302-4
• Synonyms gene
  • MIRN1302-4
• Synonyms
  • hsa-mir-1302-4
• Locus
  2q33.3
• Discovery year
  2008-11-03
• Entrez gene record
  100302130
• RefSeq identity
  • NR_031633
• Classification
  • MicroRNA MIR1302 family

Gene info

• Identity
  HGNC:37522
• Gene
  PIRC18
• Long gene name
  piwi-interacting RNA cluster 18
• Locus
  4
• Discovery year
  2009-11-05
• Entrez gene record
  100313906
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:37520
• Gene
  PIRC16
• Long gene name
  piwi-interacting RNA cluster 16
• Locus
  4
• Discovery year
  2009-11-05
• Entrez gene record
  100313849
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

Gene info

• Identity
  HGNC:32992
• Gene
  SNORD114-4
• Long gene name
  small nucleolar RNA, C/D box 114-4
• Synonyms
  • 14q(II-4)
• Locus
  14q32.31
• Discovery year
  2006-09-26
• Entrez gene record
  767580
• Pubmed identfication
  • 12045206
• RefSeq identity
  • NR_003196.1
• Classification
  • Small nucleolar RNAs, C/D box

Gene info

• Identity
  HGNC:33687
• Gene
  MIR941-4
• Long gene name
  microRNA 941-4
• Synonyms gene
  • MIRN941-4
• Synonyms
  • hsa-mir-941-4
• Locus
  20q13.33
• Discovery year
  2007-10-24
• Entrez gene record
  100126330
• RefSeq identity
  • NR_040032
• Classification
  • MicroRNAs

Gene info

• Identity
  HGNC:5809
• Gene
  IGKV2OR2-4
• Long gene name
  immunoglobulin kappa variable 2/OR2-4 (pseudogene)
• Synonyms gene name
  • immunoglobulin kappa variable 2/OR2-4
  • immunoglobulin kappa variable 2/OR2-4 pseudogene
• Synonyms
  • IGKV2/OR2-4
• GenBank acession
  • X51883
• Locus
  2q11.2
• Discovery year
  2000-04-18
• Entrez gene record
  28858
• Pubmed identfication
  • 2111145
• Classification
  • Immunoglobulin kappa (IGK) orphons

Gene info

• Identity
  HGNC:43603
• Gene
  ANKRD20A12P
• Long gene name
  ankyrin repeat domain 20 family member A12, pseudogene
• Synonyms gene name
  • ankyrin repeat domain 20 family, member A12, pseudogene
• Locus
  4
• Discovery year
  2011-11-23
• Entrez gene record
  100874392

Gene info

• Identity
  HGNC:37521
• Gene
  PIRC17
• Long gene name
  piwi-interacting RNA cluster 17
• Locus
  4
• Discovery year
  2009-11-05
• Entrez gene record
  100313809
• Pubmed identfication
  • 17881367
• Classification
  • Piwi-interacting RNA clusters

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