Hspa1b Polyclonal Antibody

• Catalog number
  CAC07358
• Price
  Please ask
• Size
  100 μg

• Other name
  Heat shock 70 kDa protein 1B,Hspa1b,Hcp70.1,Hsp70-1,Hsp70a1,Hspa1,Heat shock 70 kDa protein 1,HSP70.1
• Immunogen
  Recombinant mouse Heat shock 70 kDa protein 1B protein (2-642AA)
• Verified reactivity
  Mouse, Human
• Verified applications
  ELISA,WB. Recommended dilution:WB:1:500-2000
• Raised in
  Rabbit
• Clonality
  Polyclonal
• Protein number
  P17879
• Gene number
  Please refer to GenBank
• NCBI number
  Please refer to NCBI
• Purity
  Caprylic Acid Ammonium Sulfate Precipitation Purified
• Storage recommendation
  Aliquot and store at -20°C. Minimize freezing and thawing.
• Use before
  1 year
• Shipping requirements
  Blue ice
• Estimated production time
  3-7 business days
• Supplementary information
  In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. Essential for STUB1-mediated ubiquitination and degradation of FOXP3 in regulatory T-cells (Treg) during inflammation.
• Notes
  For research use only. Not for diagnostic procedures.
• Hyperlink
• Properties
  If you buy Antibodies supplied by bioma they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Group
  Polyclonals and antibodies
• About
  Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
• French translation
  anticorps

• Gene target
  Hspa1b  
• Gene symbol
  HSPA1B
• Short name
  Hspa1b Polyclonal Antibody
• Technique
  Polyclonal, Antibody, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Label
  Unconjugated
• Alternative name
  heat shock 70kDa protein 1B polyclonal (antibody to-)
• Alternative technique
  polyclonals, antibodies
• Alternative to gene target
  heat shock 70kDa protein 1B, HEL-S-103 and HSP70-1 and HSP70-1A and HSP70-1B and HSP70-2 and HSP70I and HSP72 and HSPA1, HSPA1B and IDBG-79309 and ENSG00000204388 and 3303,3304, ATPase activity, nuclei

Gene info

• Identity
  HGNC:5233
• Gene
  HSPA1B
• Long gene name
  heat shock protein family A (Hsp70) member 1B
• Synonyms gene name
  • heat shock 70kD protein 1B
  • heat shock 70kDa protein 1B
• Synonyms
  • HSP70-2
• Locus
  6p21.33
• Discovery year
  1995-08-11
• Entrez gene record
  3304
• Pubmed identfication
  • 1700760
• Classification
  • TIM23 complex
  • Heat shock 70kDa proteins
• VEGA ID
  OTTHUMG00000031202

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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