BMS-708163

• Catalog number
  B1622-25
• Price
  Please ask
• Size
  25 mg

• Alternative_name
  BMS-708163, BMS708163, BMS 708163, Avagacestat, γ-secretase inhibitor, (2R)-2-(N-(2-fluoro-4-(1,2,4-oxadiazol-3-yl)benzyl)-4-chlorophenylsulfonamido)-5,5,5-trifluoropentanamide
• Description
  BMS-708163 is a potent, selective γ-secretase inhibitor of Aβ40 and Aβ42 with IC50 of 0.3 nM and 0.27 nM, respectively
• CAS Number
  1146699-66-2
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₀H₁₇ClF₄N₄O₄S
• Molecular Weight
  520.88
• Cell Permeable
  Yes
• Purity
  >98%
• Solubilities
  DMSO
• Handling
  Protect from air and light
• Tag Line
  A potent, selective γ-secretase inhibitor
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• MDL Number
  MFCD13195458
• PubChem CID
  46883536
• PubChem CID Link
• SMILES
  C1=CC(=CC=C1S(=O)(=O)N(CC2=C(C=C(C=C2)C3=NOC=N3)F)C(CCC(F)(F)F)C(=O)N)Cl
• InChi
  1S/C20H17ClF4N4O4S/c21-14-3-5-15(6-4-14)34(31,32)29(17(18(26)30)7-8-20(23,24)25)10-13-2-1-12(9-16(13)22)19-27-11-33-28-19/h1-6,9,11,17H,7-8,10H2,(H2,26,30)/t17-/m1/s1
• InChi Key
  XEAOPVUAMONVLA-QGZVFWFLSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  BMS-708163  
• Short name
  BMS-708163
• Alternative name
  BMS-708163

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