-
Immunogen
A phospho-specific peptide corresponding to residues surrounding Tyr713 and Ser716 of human FES (AA711-720)
-
Antibody s target
Human FES (pTyr713 + pSer716)
-
Antibody s full description
Rabbit Anti-Human FES (pTyr713 + pSer716) Polyclonal
-
Antibody s category
Polyclonal Antibodies
-
Antibody s other name
FPS Antibody, c-fes/fps protein Antibody, cFES Antibody, FES Antibody, Feline sarcoma (Snyder Theilen) viral (v fes)/Fujinami avian sarcoma (PRCII) viral (v fps) oncogene homolog Antibody, feline sarcoma (Snyder-Theilen) viral (v-fes)/Fujinami Antibody, Feline sarcoma oncogene Antibody, FES proto oncogene tyrosine kinase Antibody, FES_HUMAN Antibody, Oncogene FES Antibody, P93c fes Antibody, Proto oncogene tyrosine protein kinase, Fes/Fps Antibody, Proto-oncogene c-Fes Antibody, Proto-oncogene c-Fps Antibody, Tyrosine-protein kinase Fes/Fps Antibody
-
Verified applications
WB, AM
-
Raised in
Rabbit
-
Antibody s reactivity
Human
-
Antibody s recommended dilutions for use
WB (1:250); optimal dilutions for assays should be determined by the user.
-
Antibody s purified from
Peptide Affinity Purified
-
Recommended buffer for storage
PBS pH7.4, 50% glycerol, 0.025% Thimerosal
-
Antibody s concentration
See included datasheet or contact our support service
-
Antibody s specificity
Detects 93.471 kDa.
-
Storage recommendations
-20°C
-
Shipping recommendations
Blue Ice or 4°C
-
Certificate of analysis
A 1:250 dilution of SPC-980 was sufficient for detection of FES (pTyr713 + pSer716) in 10 µg of human placenta lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
-
Antibody in cell
Cell Junctions, Focal Adhesion, Cell Membrane, Cytoplasm, Cytosol, Golgi Apparatus
-
Tissue specificity
See included datasheet or contact our support service.
-
Scientific context
FES is a protein-tyrosine kinase is expressed in macrophages and is thought to be involved in the regulation of myeloid differentiation. Fes has several characteristics typical of a cytoplasmic class of protein tyrosine kinases, including an SH2 domain and autophosphorylation capabilities. Fes has been shown to associate with IL-4 and several hematopoietic cytokine receptors, as well as with BCR. Phosphorylation of BCR by Fes induces the association of BCR with the Ras guanine nucleotide exchange factor complex GRB2/Sos.
-
Bibliography
Refer to PubMed
-
Released date
29/Aug/2016
-
NCBI number
NP_001996
-
Gene number
2243
-
Protein number
P07332
-
PubMed number
Refer to PubMed
-
Tested applications
To be tested
-
Tested reactivity
To be tested
-
Antibody s datasheet
Contact our support service to receive datasheet or other technical documentation.
-
Representative figure link
No Data Available
-
Warning information
Non-hazardous
-
Country of production
Canada
-
Total weight kg
1.4
-
Net weight g
0.1
-
Stock availabilit
In Stock
-
-
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
-
Test
StressMark antibodies supplies antibodies that are for research of human proteins.
-
Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
-
Group
Polyclonals and antibodies
-
About
Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera. Rabbits are used for polyclonal antibody production by StressMark antibodies. Rabbit antibodies are very stable and can be stored for several days at room temperature. StressMark antibodies adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.
-
Latin name
Oryctolagus cuniculus
-
Gene target
-
Gene symbol
FES, APC
-
Short name
Rabbit Anti- FES (pTyr713 + pSer716) Polyclonal: APC
-
Technique
anti-Human, Polyclonal, Rabbit, anti-, anti, antibody to, antibodies, antibodies against human proteins, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
-
Host
Rabbit, Rabbits
-
Isotype
Immunoglobulin
-
Label
APC
-
Species
Human, Humans
-
Alternative name
production species: rabbit Antibody toHuman FES (pTyr713 + pSer716) polyclonal: adenomatous polyposis coli
-
Alternative technique
polyclonals, rabbit-anti, antibodies
-
Alternative to gene target
adenomatous polyposis coli, BTPS2 and DP2 and DP2.5 and DP3 and GS and PPP1R46, APC and IDBG-37007 and ENSG00000134982 and 324, microtubule plus-end binding, nuclei, Apc and IDBG-134573 and ENSMUSG00000005871 and 11789, BT.25770 and IDBG-644937 and ENSBTAG00000018852 and 533233
-