anti- MCL1 antibody
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Catalog numberFNab05052
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PricePlease ask
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Size2X100μg
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Formliquid
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PurificationImmunogen affinity purified
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Purity≥95% as determined by SDS-PAGE
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StoragePBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
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BackgroundThis gene encodes an anti- apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing.
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Immunogenmyeloid cell leukemia sequence 1 (BCL2-related)
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SynonymsBCL2L3
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Calculated MW37 kDa
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Uniprot IDQ07820
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SpecificityHuman, Mouse
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Tested ApplicationELISA, WB, IHC
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Recommended dilutionWB: 1:500 - 1:2000; IHC: 1:100 - 1:200
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Image1Immunohistochemistry of paraffin-embedded human gastric cancer using FNab05052( MCL1 Antibody) at dilution of 1:100
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Image4Raji cells were subjected to SDS PAGE followed by western blot with FNab05052(MCL1 antibody) at dilution of 1:1000
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DescriptionThis antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
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PropertiesIf you buy Antibodies supplied by FineTest they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolMCL1
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Short nameanti- MCL1 antibody
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TechniqueAntibody, anti, antibody to, antibodies against human proteins, antibodies for
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HostRabbit
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IsotypeIgG
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Alternative nameantibody to- myeloid cell leukemia sequence 1 (BCL2-related) (antibody to-)
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Alternative techniqueantibodies
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Alternative to gene targetmyeloid cell leukemia sequence 1 (BCL2-related), bcl2-L-3 and BCL2L3 and EAT and Mcl-1 and MCL1-ES and mcl1/EAT and MCL1L and MCL1S and TM, MCL1 and IDBG-102145 and ENSG00000143384 and 4170, BH3 domain binding, nuclei, Mcl1 and IDBG-173221 and ENSMUSG00000038612 and 17210
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Gene info
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Identity
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Gene
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Long gene nameMCL1 apoptosis regulator, BCL2 family member
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Synonyms gene name
- myeloid cell leukemia sequence 1 (BCL2-related)
- myeloid cell leukemia 1
- MCL1, BCL2 family apoptosis regulator
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Synonyms
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GenBank acession
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Locus
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Discovery year1993-11-09
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- BCL2 family
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data