MARCKS Antibody

• Catalog number
  F48081-0.4ML
• Price
  Please ask
• Size
  0.4 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  MARCKS
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, ELISA
• Recommended dilutions
  Western blot: 1:1000
• Notes
  Titration of the MARCKS antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This MARCKS antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  P29966
• Purity
  Purified
• Description
  MARCKS is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.
• Immunogen
  A portion of amino acids 241-271 from the human protein was used as the immunogen for this MARCKS antibody.
• Storage
  Aliquot the MARCKS antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  MARCKS  
• Gene symbol
  MARCKS
• Short name
  Anti-MARCKS
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to MARCKS
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:6759
• Gene
  MARCKS
• Long gene name
  myristoylated alanine rich protein kinase C substrate
• Synonyms gene
  • MACS
• Synonyms gene name
  • myristoylated alanine-rich protein kinase C substrate (MARCKS, 80K-L)
• Synonyms
  • PKCSL
  • 80K-L
• GenBank acession
  • M68956
• Locus
  6q21
• Discovery year
  1990-01-05
• Entrez gene record
  4082
• Pubmed identfication
  • 1560845
  • 8420923
• RefSeq identity
  • NM_002356
• VEGA ID
  OTTHUMG00000188327

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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