EZSolution™ Torin 2

• Catalog number
  2354-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  9-(6-Amino-3-pyridinyl)-1-[3-(trifl­uoromethyl)phenyl]-benzo[h]-1,6-naphthyridin-2(1H)­-one
• Description
  A potent, selective and ATP-competitive mTOR inhibitor (IC₅₀ = 2.1 nM for mTORC1). Torin 2 displays 800-fold selectivity for mTOR over PI3K (cellular EC₅₀ values of 0.25 nM and 200 nM, respectively) and exhibits 100-fold binding selectivity relative to 440 other protein kinases.
• CAS Number
  1223001-51-1
• Structure Available
  Yes
• Salt Form
  No
• Molecular Formula
  C₂₄H₁₅F₃N₄O
• Molecular Weight
  432.4
• Cell Permeable
  Yes
• Purity
  ≥98% by HPLC
• Handling
  Protect from light and moisture
• Tag Line
  A potent mTOR inhibitor
• Storage Condition
  -20 ̊C
• Shipping Condition
  gel pack
• Shelf Life
  12 months
• MDL Number
  MFCD18782652
• PubChem CID
  51358113
• PubChem CID Link
• SMILES
  C1=CC(=CC(=C1)N2C(=O)C=CC3=CN=C4C=CC(=CC4=C32)C5=CN=C(C=C5)N)C(F)(F)F
• InChi
  InChI=1S/C24H15F3N4O/c25-24(26,27)17-2-1-3-18(11-17)31-22(32)9-6-16-13-29-20-7-4-14(10-19(20)23(16)31)15-5-8-21(28)30-12-15/h1-13H,(H2,28,30)
• InChi Key
  GUXXEUUYCAYESJ-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  EZSolution™   Torin  
• Short name
  EZSolution™ Torin 2
• Alternative name
  EZSolution™ Torin 2

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