Thioredoxin isoform 1 (Trx), Active, Human Recombinant
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Catalog number
P1039-100
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Price
Please ask
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Size
100 ug
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Synonyms
TXN, TRX, TRX1, Thioredoxin 1
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Alternative_names
TXN, TRX, TRX1, Thioredoxin 1
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Description
A protein involved in redox signaling
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Recombinant
Yes
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Source
E. coli
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Purity by SDS PAGE
≥95%
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Assay
SDS-PAGE
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Activity Specifications test method
Measured by its ability to reduce FITC-labeled oxidized glutathione (FITC-GSSG-FITC) to FITC-labeled reduced glutathione (FITC-GSH).
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Biological activity
This enzyme has activity ≥20 mU/mg based on its ability to reduce FITC-labeled oxidized glutathione (FITC-GSSG-FITC) to FITC-labeled reduced glutathione (FITC-GSH).
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Results
Enzymatic activity is ≥20 U/mg
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Molecular Weight
14.5 kDa (130 aa)
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Storage Temp
4°C
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Shipping
Gel Pack
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Shelf Life
12 months
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Appearance
Lyophilized
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Reconstitution Instructions
Reconstitute in deionized water.
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Background Information
Thioredoxin (Trx) is a disulfide reductase that reduces disulfide bonds into thiol groups through a thiol-disulfide exchange with its target proteins to regulate oxidative stress and redox signaling. Trx activity is dependent on NADPH and Thioredoxin Reductase’s (TrxR) ability to reduce it at Cysteine 32 and Cysteine 35.
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Handling
Centrifuge the vial prior to opening.
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Usage
For Research Use Only! Not to be used in humans
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Properties
Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Additional source
Recombinants or rec. proteins
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Group
recombinants
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Gene target
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Short name
Thioredoxin isoform 1 (Trx), Active, Recombinant
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Technique
Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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Species
Human, Humans
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Alternative name
Thioredoxin isoform 1 (Trx), functionnal, H. sapiens Rec.
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Alternative technique
rec
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MeSH Data
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Name
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Concept
Scope note:
The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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