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Alternative_name
L 163191, Ibutamoren, MK0677, 2-amino-2-methyl-N-[(2R)-1-(1-methylsulfonylspiro[2H-indole-3,4'-piperidine]-1'-yl)-1-oxo-3-(phenylmethoxy)propan-2-yl]propanamide mesylate, L163191, MK-0677, L-163191
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Description
Ibutamoren is a non-peptidic, potent, long-acting, orally-active, and selective agonist of the ghrelin receptor and a growth hormone secretagogue. It mimicks the growth hormone (GH)-stimulating action of the endogenous hormone ghrelin. It stimulates GH release from rat pituitary cells in vitro (EC50 = 1.3 nM) and enhances GH plasma levels in vivo.
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CAS Number
159752-10-0
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Structure Available
Yes
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Salt Form
No
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Molecular Formula
C₂₇H₃₆N₄O₅S.CH₃SO₃H
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Molecular Weight
624.77
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Cell Permeable
True
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Purity
≥98% by HPLC
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Solubilities
Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
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Handling
Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
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Tag Line
A Ghrelin agonist
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Storage Condition
-20ºC
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Shipping Condition
Gel Pack
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Shelf Life
36 months
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PubChem CID
6450830
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SMILES
CC(C)(N)C(N[C@H](COCC1=CC=CC=C1)C(N2CCC3(CC2)CN(S(=O)(C)=O)C4=C3C=CC=C4)=O)=O.OS(=O)(C)=O
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InChi
InChI=1S/C27H36N4O5S.CH4O3S/c1-26(2,28)25(33)29-22(18-36-17-20-9-5-4-6-10-20)24(32)30-15-13-27(14-16-30)19-31(37(3,34)35)23-12-8-7-11-21(23)27;1-5(2,3)4/h4-12,22H,13-19,28H2,1-3H3,(H,29,33);1H3,(H,2,3,4)/t22-;/m1./s1
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InChi Key
DUGMCDWNXXFHDE-VZYDHVRKSA-N
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MSDS Available
False