YH239-EE
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Catalog numberB1229-5
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PricePlease ask
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Size5 mg
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Alternative_name6-Chloro-3-[1-[[(4-chlorophenyl)methyl]formylamino]-2-[(1,1-dimethylethyl)amino]-2-oxoethyl]-1H-indole-2-carboxylic acid Ethyl Ester
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DescriptionYH239-EE is potent p53-MDM2 interaction inhibitor that induces cell cycle arrest leading to potential apoptosis by p53 activation and downstream target in AML cells with p53 mutation
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CAS Number1364488-67-4
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Structure AvailableYes
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Salt FormNo
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Molecular FormulaC₂₅H₂₇Cl₂N₃O₄
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Molecular Weight504.41
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesDMSO(>50 mg/ml)
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HandlingProtect from air and light
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Tag LineA potent p53-MDM2 interaction inhibitor
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Storage Condition-20°C
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Shipping Conditiongel pack
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Shelf Life36 months
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PubChem CID56943013
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SMILESCCOC(=O)C1=C(C2=C(N1)C=C(C=C2)Cl)C(C(=O)NC(C)(C)C)N(CC3=CC=C(C=C3)Cl)C=O
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InChiInChI=1S/C25H27Cl2N3O4/c1-5-34-24(33)21-20(18-11-10-17(27)12-19(18)28-21)22(23(32)29-25(2,3)4)30(14-31)13-15-6-8-16(26)9-7-15/h6-12,14,22,28H,5,13H2,1-4H3,(H,29,32)
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InChi KeyOTUBDDRFPQLPKD-UHFFFAOYSA-N
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MSDS AvailableYes
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Gene target
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Short nameYH239-EE
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Alternative nameYH239-EE
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