YH239-EE

  • Catalog number
    B1229-5
  • Price
    Please ask
  • Size
    5 mg
  • Alternative_name
    6-Chloro-3-[1-[[(4-chlorophenyl)methyl]formylamino]-2-[(1,1-dimethylethyl)amino]-2-oxoethyl]-1H-indole-2-carboxylic acid Ethyl Ester
  • Description
    YH239-EE is potent p53-MDM2 interaction inhibitor that induces cell cycle arrest leading to potential apoptosis by p53 activation and downstream target in AML cells with p53 mutation
  • CAS Number
    1364488-67-4
  • Structure Available
    Yes
  • Salt Form
    No
  • Molecular Formula
    C₂₅H₂₇Cl₂N₃O₄
  • Molecular Weight
    504.41
  • Cell Permeable
    Yes
  • Purity
    ≥98% by HPLC
  • Solubilities
    DMSO(>50 mg/ml)
  • Handling
    Protect from air and light
  • Tag Line
    A potent p53-MDM2 interaction inhibitor
  • Storage Condition
    -20°C
  • Shipping Condition
    gel pack
  • Shelf Life
    36 months
  • PubChem CID
    56943013
  • SMILES
    CCOC(=O)C1=C(C2=C(N1)C=C(C=C2)Cl)C(C(=O)NC(C)(C)C)N(CC3=CC=C(C=C3)Cl)C=O
  • InChi
    InChI=1S/C25H27Cl2N3O4/c1-5-34-24(33)21-20(18-11-10-17(27)12-19(18)28-21)22(23(32)29-25(2,3)4)30(14-31)13-15-6-8-16(26)9-7-15/h6-12,14,22,28H,5,13H2,1-4H3,(H,29,32)
  • InChi Key
    OTUBDDRFPQLPKD-UHFFFAOYSA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    YH239-EE
  • Alternative name
    YH239-EE
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