PF-06447475
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Catalog number9447-5
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PricePlease ask
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Size5 mg
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Alternative_name3-(4-morpholino-7H-pyrrolo[2,3-d]pyrimidin-5-yl)benzonitrile
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DescriptionPF-06447475 is a highly potent, selective, brain-permeable, and in vivo active LRRK2 (Leucine rich repeat kinase 2) kinase inhibitor. Could be potentially useful in the treatment of Parkinson’s disease (PD).
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CAS Number1527473-33-1
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Structure AvailableYes
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Molecular FormulaC₁₇H₁₅N₅O
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Molecular Weight305.33
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Cell PermeableYes
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Purity≥98% by HPLC
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SolubilitiesDMSO (~10 mg/ml)
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HandlingProtect from air and light
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Tag LineA LRRK2 (Leucine rich repeat kinase 2) kinase inhibitor
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Storage Condition-20°C
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Shipping ConditionGel pack
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Shelf Life36 months
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PubChem CID72706840
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SMILESC1COCCN1C2=NC=NC3=C2C(=CN3)C4=CC=CC(=C4)C#N
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InChiInChI=1S/C17H15N5O/c18-9-12-2-1-3-13(8-12)14-10-19-16-15(14)17(21-11-20-16)22-4-6-23-7-5-22/h1-3,8,10-11H,4-7H2,(H,19,20,21)
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InChi KeyBHTWDJBVZQBRKP-UHFFFAOYSA-N
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MSDS AvailableYes
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Gene target
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Short namePF-06447475
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Alternative namePF-06447475
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