PF-06447475

  • Catalog number
    9447-5
  • Price
    Please ask
  • Size
    5 mg
  • Alternative_name
    3-(4-morpholino-7H-pyrrolo[2,3-d]pyrimidin-5-yl)benzonitrile
  • Description
    PF-06447475 is a highly potent, selective, brain-permeable, and in vivo active LRRK2 (Leucine rich repeat kinase 2) kinase inhibitor. Could be potentially useful in the treatment of Parkinson’s disease (PD).
  • CAS Number
    1527473-33-1
  • Structure Available
    Yes
  • Molecular Formula
    C₁₇H₁₅N₅O
  • Molecular Weight
    305.33
  • Cell Permeable
    Yes
  • Purity
    ≥98% by HPLC
  • Solubilities
    DMSO (~10 mg/ml)
  • Handling
    Protect from air and light
  • Tag Line
    A LRRK2 (Leucine rich repeat kinase 2) kinase inhibitor
  • Storage Condition
    -20°C
  • Shipping Condition
    Gel pack
  • Shelf Life
    36 months
  • PubChem CID
    72706840
  • SMILES
    C1COCCN1C2=NC=NC3=C2C(=CN3)C4=CC=CC(=C4)C#N
  • InChi
    InChI=1S/C17H15N5O/c18-9-12-2-1-3-13(8-12)14-10-19-16-15(14)17(21-11-20-16)22-4-6-23-7-5-22/h1-3,8,10-11H,4-7H2,(H,19,20,21)
  • InChi Key
    BHTWDJBVZQBRKP-UHFFFAOYSA-N
  • MSDS Available
    Yes
  • Gene target
  • Short name
    PF-06447475
  • Alternative name
    PF-06447475
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