LY3023414

Alternative_name

LY3023414, LY-3023414; LY 3023414; (S)-8-(5-(2-hydroxypropan-2-yl)pyridin-3-yl)-1-(2-methoxypropyl)-3-methyl-1,3-dihydro-2H-imidazo[4,5-c]quinolin-2-one; 8-[5-(2-hydroxypropan-2-yl)pyridin-3-yl]-1-[(2S)-2-methoxypropyl]-3-methylimidazo[4,5-c]quinolin-2-one
Description

LY3023414 is a small molecule that has been shown in vitro to be a selective ATP-competitive inhibitor of PI3Kα and mTOR, DNA-PK, and other class I PI3K family members.
CAS Number

1386874-06-1
Structure Available

Yes
Salt Form

No
Molecular Formula

C₂₃H₂₆N₄O₃
Molecular Weight

406.48
Cell Permeable

Yes
Purity

>98%
Solubilities

DMSO
Handling

Protect from air and light
Tag Line

A selective ATP-competitive inhibitor of PI3Kα and mTOR, DNA-PK, and other class I PI3K family members
Storage Condition

-20°C
Shipping Condition

gel pack
Shelf Life

36 months
PubChem CID

57519748
PubChem CID Link
SMILES

CC(CN1C2=C3C=C(C=CC3=NC=C2N(C1=O)C)C4=CC(=CN=C4)C(C)(C)O)OC
InChi

InChI=1S/C23H26N4O3/c1-14(30-5)13-27-21-18-9-15(16-8-17(11-24-10-16)23(2,3)29)6-7-19(18)25-12-20(21)26(4)22(27)28/h6-12,14,29H,13H2,1-5H3/t14-/m0/s1
InChi Key

ACCFLVVUVBJNGT-AWEZNQCLSA-N
Data Sheet Link
MSDS Available

Yes