Tanshinone IIA-Sulfonic Sodium
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Catalog number
B1902-25
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Price
Please ask
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Size
25 mg
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Alternative_name
Sodium tanshinone IIA sulfonate; Sulfotanshinone sodium II-A; T06
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Description
Sodium tanshinone IIA sulphonate (T06) is a water-soluble derivative of tanshinone IIA, that displays versatile biological properties. Recently, it has been shown to act as an ectosteric inhibitor of cathepsin K (CatK). T06 binds in an ectosteric side of Cathepsin K remote from its active site and selectively inhibits collagen degradation. It also inhibits bone resorption in ovariectomized mice.
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CAS Number
69659-80-9
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Structure Available
Yes
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Salt Form
No
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Molecular Formula
C₁₉H₁₇NaO₆S
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Molecular Weight
396.39
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Cell Permeable
Yes
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Purity
≥98% by HPLC
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Solubilities
DMSO or H₂O (~5 mg/ml)
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Handling
Protect from air and light
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Tag Line
A potent ectosteric inhibitor of cathepsin K (CatK)
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Storage Condition
-20°C
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Shipping Condition
gel pack
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Shelf Life
36 months
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MDL Number
MFCD09028094
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PubChem CID
23669322
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SMILES
CC1=C(OC2=C1C(=O)C(=O)C3=C2C=CC4=C3CCCC4(C)C)S(=O)(=O)[O-].[Na+]
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InChi
InChI=1S/C19H18O6S.Na/c1-9-13-15(20)16(21)14-10-5-4-8-19(2,3)12(10)7-6-11(14)17(13)25-18(9)26(22,23)24;/h6-7H,4-5,8H2,1-3H3,(H,22,23,24);/q;+1/p-1
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InChi Key
AZEZEAABTDXEHR-UHFFFAOYSA-M
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MSDS Available
Yes
Gene info
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Identity
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Gene
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Long gene name
myosin heavy chain 2
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Synonyms gene
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Synonyms gene name
- myosin, heavy polypeptide 2, skeletal muscle, adult
- inclusion body myopathy 3, autosomal dominant
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Synonyms
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Locus
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Discovery year
2001-06-22
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Myosin heavy chains, class II
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VEGA ID
Product images
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